Point of care testing for infectious diseases

H Chen, K Liu, Z Li, P Wang - Clinica chimica acta, 2019 - Elsevier
Infectious diseases are caused by pathogenic microorganisms and can be transmitted
between individuals and populations thus threatening the general public health and …

Recent developments in magnetic diagnostic systems

H Lee, TH Shin, J Cheon, R Weissleder - Chemical reviews, 2015 - ACS Publications
Rapid point-of-care (POC) diagnostics that enable specific cellular and molecular detection
are currently being developed while some have already become clinical reality. These …

Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic …

JG Peter, LS Zijenah, D Chanda, P Clowes, M Lesosky… - The Lancet, 2016 - thelancet.com
Background HIV-associated tuberculosis is difficult to diagnose and results in high mortality.
Frequent extra-pulmonary presentation, inability to obtain sputum, and paucibacillary …

Plasmonic-based platforms for diagnosis of infectious diseases at the point-of-care

Z Li, L Leustean, F Inci, M Zheng, U Demirci… - Biotechnology …, 2019 - Elsevier
Infectious diseases such as HIV-1/AIDS, tuberculosis (TB), hepatitis B (HBV), and malaria
still exert a tremendous health burden on the developing world, requiring rapid, simple and …

Results from early programmatic implementation of Xpert MTB/RIF testing in nine countries

J Creswell, AJ Codlin, E Andre, MA Micek… - BMC infectious …, 2014 - Springer
Abstract Background The Xpert MTB/RIF assay has garnered significant interest as a
sensitive and rapid diagnostic tool to improve detection of sensitive and drug resistant …

Xpert MTB/RIF results in patients with previous tuberculosis: can we distinguish true from false positive results?

G Theron, R Venter, G Calligaro, L Smith… - Clinical Infectious …, 2016 - academic.oup.com
Background. Patients with previous tuberculosis may have residual DNA in sputum that
confounds nucleic acid amplification tests such as Xpert MTB/RIF. Little is known about the …

[HTML][HTML] Point of care diagnostics for tuberculosis

AL García-Basteiro, A DiNardo, B Saavedra, DR Silva… - Pulmonology, 2018 - Elsevier
The goals of the End TB strategy, which aims to achieve a 90% reduction in tuberculosis
(TB) incidence and a 95% reduction in TB mortality by 2035, will not be achieved without …

Do high rates of empirical treatment undermine the potential effect of new diagnostic tests for tuberculosis in high-burden settings?

G Theron, J Peter, D Dowdy, I Langley… - The Lancet infectious …, 2014 - thelancet.com
In tuberculosis-endemic settings, patients are often treated empirically, meaning that they
are placed on treatment based on clinical symptoms or tests that do not provide a …

Detection of tuberculosis by automatic cough sound analysis

GHR Botha, G Theron, RM Warren… - Physiological …, 2018 - iopscience.iop.org
Objective: Globally, tuberculosis (TB) remains one of the most deadly diseases. Although
several effective diagnosis methods exist, in lower income countries clinics may not be in a …

[HTML][HTML] Multidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challenges

G Günther - Clinical medicine, 2014 - Elsevier
Multidrug-resistant and extensively drug-resistant tuberculosis are recent global health
issues, which makes tuberculosis–after the success of short course treatment during the …