[HTML][HTML] Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023 - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

[HTML][HTML] A pan-cancer single-cell panorama of human natural killer cells

F Tang, J Li, L Qi, D Liu, Y Bo, S Qin, Y Miao, K Yu… - Cell, 2023 - cell.com
Natural killer (NK) cells play indispensable roles in innate immune responses against tumor
progression. To depict their phenotypic and functional diversities in the tumor …

[HTML][HTML] Single-cell atlas of healthy human blood unveils age-related loss of NKG2C+ GZMB− CD8+ memory T cells and accumulation of type 2 memory T cells

M Terekhova, A Swain, P Bohacova, E Aladyeva… - Immunity, 2023 - cell.com
Extensive, large-scale single-cell profiling of healthy human blood at different ages is one of
the critical pending tasks required to establish a framework for the systematic understanding …

[HTML][HTML] Natural killer cells in aging and age-related diseases

C Qi, Q Liu - Neurobiology of Disease, 2023 - Elsevier
Aging leads to escalated systemic inflammation. As the sentinel of immune system, natural
killer (NK) cells are early responders that sense cues and signals from target organs and …

[HTML][HTML] New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine

H Xu, S Lin, Z Zhou, D Li, X Zhang, M Yu… - Cellular & Molecular …, 2023 - nature.com
Over the past thirty years, the importance of chemokines and their seven-transmembrane G
protein-coupled receptors (GPCRs) has been increasingly recognized. Chemokine …

[HTML][HTML] Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents

Z Li, X Chen, J Dan, T Hu, Y Hu, S Liu, Y Chai… - Signal transduction and …, 2022 - nature.com
SARS-CoV-2 Omicron variant infection generally gives rise to asymptomatic to moderate
COVID-19 in vaccinated people. The immune cells can be reprogrammed or “imprinted” by …

[HTML][HTML] Age-dependent NK cell dysfunctions in severe COVID-19 patients

C Fionda, S Ruggeri, G Sciumè, M Laffranchi… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are key innate effectors of antiviral immune response, and their
activity changes in ageing and severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Systems analysis of human innate immunity in COVID-19

S Müller, JL Schultze - Seminars in immunology, 2023 - Elsevier
Recent developments in sequencing technologies, the computer and data sciences, as well
as increasingly high-throughput immunological measurements have made it possible to …

[HTML][HTML] Integrated Analysis of Single-Cell and Bulk RNA Sequencing Data Reveals Memory-like NK Cell Subset Associated with Mycobacterium tuberculosis …

M Shekarkar Azgomi, GD Badami, M Lo Pizzo… - Cells, 2024 - mdpi.com
Natural killer (NK) cells are innate-like lymphocytes that belong to the family of type-1 innate
lymphoid cells and rapidly respond to virus-infected and tumor cells. In this study, we have …