[HTML][HTML] Microtubular dysfunction and male infertility
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being
vital for organelle transport and cellular divisions during spermatogenesis and sperm motility …
vital for organelle transport and cellular divisions during spermatogenesis and sperm motility …
[HTML][HTML] Signaling pathways regulating blood–tissue barriers—Lesson from the testis
Q Wen, EI Tang, Y Gao, TT Jesus, DS Chu… - … Et Biophysica Acta (BBA …, 2018 - Elsevier
Signaling pathways that regulate blood–tissue barriers are important for studying the biology
of various blood–tissue barriers. This information, if deciphered and better understood, will …
of various blood–tissue barriers. This information, if deciphered and better understood, will …
[PDF][PDF] Dissecting mammalian spermatogenesis using spatial transcriptomics
Single-cell RNA sequencing has revealed extensive molecular diversity in gene programs
governing mammalian spermatogenesis but fails to delineate their dynamics in the native …
governing mammalian spermatogenesis but fails to delineate their dynamics in the native …
Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity
X Cao, L Shen, C Yan, Y Zhou, G Xiong, Y Wang, Y Liu… - Toxicology letters, 2017 - Elsevier
Blood-testis barrier (BTB) provides a suitable microenvironment for germ cells that is
required for spermatogenesis. Exposure to particulate matter (PM) is recognized to occasion …
required for spermatogenesis. Exposure to particulate matter (PM) is recognized to occasion …
Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis
Germ cell differentiation during the epithelial cycle of spermatogenesis is accompanied by
extensive remodeling at the Sertoli cell–cell and Sertoli cell–spermatid interface to …
extensive remodeling at the Sertoli cell–cell and Sertoli cell–spermatid interface to …
Defects of microtubule cytoskeletal organization in NOA human testes
X Wu, D Yun, M Sang, J Liu, L Zhou, J Shi… - Reproductive Biology …, 2022 - Springer
The importance of actin and microtubule (MT) cytoskeletons in testis function in rodents is
known to some extent, but its role in the etiology of azoospermia in humans remains …
known to some extent, but its role in the etiology of azoospermia in humans remains …
Mechanistic insights into PFOS-mediated Sertoli cell injury
B Mao, D Mruk, Q Lian, R Ge, C Li, B Silvestrini… - Trends in molecular …, 2018 - cell.com
Studies have proven that per-and polyfluoroalkyl substances are harmful to humans, most
notably perfluorooctanesulfonate (PFOS). PFOS induces rapid disorganization of actin-and …
notably perfluorooctanesulfonate (PFOS). PFOS induces rapid disorganization of actin-and …
[HTML][HTML] F5-peptide induces aspermatogenesis by disrupting organization of actin-and microtubule-based cytoskeletons in the testis
During the release of sperm at spermiation, a biologically active F5-peptide, which can
disrupt the Sertoli cell tight junction (TJ) permeability barrier, is produced at the site of the …
disrupt the Sertoli cell tight junction (TJ) permeability barrier, is produced at the site of the …
[HTML][HTML] Regulation of the blood–testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane
Laminin α2 is one of the constituent components of the basement membrane (BM) in adult
rat testes. Earlier studies that used a mouse genetic model have shown that a deletion of …
rat testes. Earlier studies that used a mouse genetic model have shown that a deletion of …
Regulation of blood-testis barrier (BTB) dynamics, role of actin-, and microtubule-based cytoskeletons
Q Wen, EI Tang, N Li, DD Mruk, WM Lee… - Sertoli Cells: Methods …, 2018 - Springer
The blood-testis barrier (BTB) is an important ultrastructure in the testis that supports meiosis
and postmeiotic spermatid development since a delay in the establishment of a functional …
and postmeiotic spermatid development since a delay in the establishment of a functional …