The importance of actin and microtubule (MT) cytoskeletons in testis function in rodents is
known to some extent, but its role in the etiology of azoospermia in humans remains …

Laminin α2 is one of the constituent components of the basement membrane (BM) in adult
rat testes. Earlier studies that used a mouse genetic model have shown that a deletion of …

The blood-testis barrier (BTB) is an important ultrastructure in the testis that supports meiosis
and postmeiotic spermatid development since a delay in the establishment of a functional …

Mammalian target of rapamycin (mTOR) is a central regulator of cellular metabolic
phenotype and is involved in virtually all aspects of cellular function. It integrates not only …

In the mammalian testis, spermatogenesis is dependent on the microtubule (MT)-specific
motor proteins, such as dynein 1, that serve as the engine to support germ cell and …

The blood-testis barrier (BTB), conferred by Sertoli cells in the mammalian testis, is an
important ultrastructure that supports spermatogenesis. Studies using animal models have …

The transport of germ cells from the base of the seminiferous epithelium toward the luminal
edge of the tubule lumen in the adluminal compartment during the epithelial cycle is an …

Studies have shown that mammalian testes, in particular the Sertoli cells, are highly
susceptible to exposure of environmental toxicants, such as cadmium …

Throughout spermatogenesis, cellular cargoes including haploid spermatids are required to
be transported across the seminiferous epithelium, either toward the microtubule (MT) plus …

In the rat testis, studies have shown that cell polarity, in particular spermatid polarity, to
support spermatogenesis is conferred by the coordinated efforts of the Par-, Crumbs-, and …