Role of microtubule+ TIPs and-TIPs in spermatogenesis–insights from studies of toxicant models

B Mao, R Ge, CY Cheng - Reproductive Toxicology, 2020 - Elsevier
During spermatogenesis, preleptotene spermatocytes and haploid spermatids, lacking
lamellipodia and filopodia to initiate cell movement per se, but rely on Sertoli cells for …

AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis

S Wu, L Li, X Wu, CKC Wong, F Sun… - The FASEB …, 2021 - Wiley Online Library
In mammalian testes, extensive remodeling of the microtubule (MT) and actin cytoskeletons
takes place in Sertoli cells across the seminiferous epithelium to support spermatogenesis …

Hydroxytyrosol Ameliorates Busulfan-Induced Oligozoospermia in a Mouse Model

T Ye, Y Ma, J Dong, Y Dong, J Hui… - Natural Product …, 2024 - journals.sagepub.com
Objective Hydroxytyrosol (HT), a polyphenolic component identified in olive oil and leaves,
represents one of the most extensively investigated natural phenol due to its diverse …

Is Parthanatos Involved in Varicocele?

K Wang, Y Gao, C Wang, Z Liu, M Liang… - DNA and Cell …, 2022 - liebertpub.com
Varicoceles (VCs) have received widespread attention as a primary factor affecting male
fertility and a pathological condition that may lead to decreased sperm count and motility in …

[HTML][HTML] A Deep Insight of Spermatogenesis and Hormone Levels of Aqua-Cultured Turbot (Scophthalmus maximus)

Y Liu, Q Liu, S Xu, Y Wang, C Feng, C Zhao… - Frontiers in Marine …, 2021 - frontiersin.org
Turbot (Scophthalmus maximus) is an important marine fish both in Europe and North
China. Although there are plenty of studies on the reproduction of turbot, the complete …

mTORC1/rpS6 and p-FAK-Y407 signaling regulate spermatogenesis: Insights from studies of the adjudin pharmaceutical/toxicant model

L Wang, L Li, X Wu, CKC Wong, A Perrotta… - Seminars in Cell & …, 2022 - Elsevier
In rodents and humans, the major cellular events at spermatogenesis include self-renewal of
spermatogonial stem cells and undifferentiated spermatogonia via mitosis, commitment of …

[HTML][HTML] NC1-peptide derived from collagen α3 (IV) chain is a blood-tissue barrier regulator: lesson from the testis

SW Liu, HT Li, RS Ge, CY Cheng - Asian Journal of Andrology, 2021 - journals.lww.com
Collagen α3 (IV) chains are one of the major constituent components of the basement
membrane in the mammalian testis. Studies have shown that biologically active fragments …

Spermiation: Insights from studies on the adjudin model

H Chen, Y Jiang, DD Mruk, CY Cheng - Molecular Mechanisms in …, 2021 - Springer
Spermatogenesis is comprised of a series of cellular events that lead to the generation of
haploid sperm. These events include self-renewal of spermatogonial stem cells (SSC) …

[HTML][HTML] Transcriptomic Interaction between Young Fecal Transplantation and Perfluorobutanesulfonate in Aged Zebrafish Gonads

L Tang, J Li, B Sun, Y Bai, X Zhou, L Chen - Toxics, 2022 - mdpi.com
The transfer of young fecal microbiota has been found to significantly refresh the
reproductive endocrine system and effectively ameliorate the toxicity of …

Environmental toxicants and cell polarity in the testis

B Mao, L Li, M Yan, Q Lian, R Ge, CY Cheng - Reproductive Toxicology, 2018 - Elsevier
During spermatogenesis, head-tail cell polarity, apico-basal cell polarity and planar cell
polarity (PCP) are remarkably noted in the seminiferous epithelium in which the heads of …