Oxidative stress, amyloid-β peptide, and altered key molecular pathways in the pathogenesis and progression of Alzheimer's disease

DA Butterfield, D Boyd-Kimball - Journal of Alzheimer's …, 2018 - content.iospress.com
Oxidative stress is implicated in the pathogenesis and progression of Alzheimer's disease
(AD) and its earlier stage, amnestic mild cognitive impairment (aMCI). One source of …

Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

DA Butterfield, T Reed, SF Newman… - Free Radical Biology and …, 2007 - Elsevier
Oxidative stress has been implicated to play a crucial role in the pathogenesis of a number
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …

[HTML][HTML] Successful cognitive and emotional aging

DV Jeste, CA Depp, IV Vahia - World psychiatry, 2010 - ncbi.nlm.nih.gov
We review the definitions, determinants, and ways of enhancing successful cognitive and
emotional aging. Objective definitions of successful aging based on physical health …

Cognitive dysfunction syndrome: a disease of canine and feline brain aging

GM Landsberg, J Nichol, JA Araujo - … Clinics of North America: Small Animal …, 2012 - Elsevier
CDS is an underdiagnosed behavioral problem that affects a substantial number of aged
pets. Because changes in behavior are often early indicators of medical or behavior …

Nutrition, brain aging, and neurodegeneration

J Joseph, G Cole, E Head, D Ingram - Journal of Neuroscience, 2009 - Soc Neuroscience
The onset of age-related neurodegenerative diseases superimposed on a declining nervous
system could enhance the motor and cognitive behavioral deficits that normally occur in …

[HTML][HTML] Canine cognitive dysfunction and Alzheimer's disease–two facets of the same disease?

S Prpar Mihevc, G Majdič - Frontiers in neuroscience, 2019 - frontiersin.org
Neurodegenerative diseases present a major and increasing burden in the societies
worldwide. With aging populations, the prevalence of neurodegenerative diseases is …

Stereotypic behaviour in captive animals: fundamentals and implications for welfare and beyond

G Mason - … animal behaviour: fundamentals and applications to …, 2006 - books.google.com
In this final chapter, I argue that stereotypic behaviour involves diverse mechanisms which
are differentially involved across different forms, which explain different aspects of the …

Redox proteomics and amyloid β‐peptide: insights into Alzheimer disease

DA Butterfield, D Boyd‐Kimball - Journal of neurochemistry, 2019 - Wiley Online Library
Alzheimer disease (AD) is a progressive neurodegenerative disorder associated with aging
and characterized pathologically by the presence of senile plaques, neurofibrillary tangles …

Cognitive aging in dogs

D Chapagain, F Range, L Huber, Z Virányi - Gerontology, 2018 - karger.com
A decline in the physical or mental health of older dogs can be a challenge for the owners,
whose relationship with their dog is compromised by the cognitive and behavioral changes …

Canine cognitive dysfunction: pathophysiology, diagnosis, and treatment

CW Dewey, ES Davies, H Xie… - … Clinics: Small Animal …, 2019 - vetsmall.theclinics.com
Canine cognitive dysfunction (CCD) is the canine analog of human Alzheimer disease (AD).
CCD is common in older dogs, particularly those more than 8 years old. Slowly progressive …