The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

Introduction: Biliary tract cancer (BTC) is a heterogeneous group of aggressive malignancies
comprising intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, gallbladder …

Introduction: The prognosis of patients with advanced biliary tract cancer (BTC) remains
dismal, with a 5-year overall survival rate of less than 10%. Although immune checkpoint …

Despite of the high lethality of gallbladder cancer (GBC), little is known regarding molecular
regulation of the tumor immunosuppressive microenvironment. Here, we determined tumor …

Simple Summary Gallbladder cancer is the most common malignancy of the biliary tract and
is associated with several risk factors such as female sex, ethnic background, and chronic …

As an emerging cancer treatment strategy, ferroptosis is distinguished by the perturbation of
lipid metabolism equilibrium and the accumulation of lipid peroxidation. However, the …

The long non-coding RNAs (lncRNAs) have been implicated in multiple human cancers,
which may offer great potential as putative targets for cancer diagnosis and treatment …

The NLRP3 inflammasome is an intracellular sensor and an essential component of the
innate immune system involved in danger recognition. An important hallmark of …

Background: Gallbladder cancer (GBC) is the most common malignant tumor of biliary tract.
Isoliquiritigenin (ISL) is a natural compound with chalcone structure extracted from the roots …

Programmed cell death (PCD) refers to cell death in a manner that depends on specific
genes encoding signals or activities. PCD includes apoptosis, pyroptosis, autophagy and …