Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune rheumatic disease
characterized by lymphoplasmacytic infiltration of the salivary and lacrimal glands, whereby …

Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Lupus is a chronic, autoimmune multisystem inflam-matory disease that is associated with
sizable morbidity and mortality. 1 When lupus commences in an individual less than 18 …

Recognising neuropsychiatric involvement by systemic lupus erythematosus (SLE) is of
growing importance, however many barriers to this exist at multiple levels of our currently …

Sjögren's syndrome is a systemic autoimmune disease characterized by immune-mediated
injury of exocrine glands, as well as a diverse array of extraglandular manifestations. B cell …

Cognitive impairment is a frequent manifestation of neuropsychiatric systemic lupus
erythematosus, present in up to 80% of patients and leading to a diminished quality of life. In …

During the last decades, there has been an increased interest in the discovery and
validation of biomarkers that reliably reflect specific aspects of lupus. Although many …

Autoimmune encephalitis encompasses a wide variety of protean pathologic processes
associated with the presence of antibodies against neuronal intracellular proteins, synaptic …

Primary Sjögren's syndrome (pSS) is a complex and heterogeneous disease. Last year, a
great deal of basic and clinical research was carried out in pSS. Following the previous …