Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle
performance, maintaining metabolic function and supporting longevity and healthspan …

Abstract Purpose of Review This article introduces the roles of perinatal DNA methylation in
human health and disease, highlights the challenges of tissue and cellular heterogeneity to …

Environmental factors can induce epigenetic alterations in the germ cells that can potentially
be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic …

Offspring of women with gestational diabetes mellitus (GDM) are at increased risk of
developing metabolic disease, potentially mediated by epigenetic mechanisms. We …

Substantial evidence indicated that maternal malnutrition could increase the susceptibility to
obesity, insulin resistance, and type 2 diabetes in adulthood. It is increasingly apparent that …

Background The association of in vitro fertilisation (IVF) and DNA methylation has been
studied predominantly at regulatory regions of imprinted genes and at just thousands of the …

Prenatal hypoxia (PH) is one of the most common stresses on fetuses, and might lead to
abnormal brain development. This work investigates whether PH affects behavioral …

Apart from direct inheritance and the effects of a shared environment, maternal health,
eating habits and diet can affect offspring health by developmental programming …

Maternal intake of dietary methyl‐micronutrients (eg folate, choline, betaine and vitamin B‐
12) during pregnancy is essential for normal maternal and fetal methionine metabolism, and …

Intrauterine growth restriction (IUGR) is associated with adverse perinatal outcomes and late-
onset diseases in offspring. Eating disorders, voluntary caloric restriction and maternal …