Fundamental Neurochemistry Review: Copper availability as a potential therapeutic target in progressive supranuclear palsy: Insight from other neurodegenerative …

JL Billings, JBW Hilton, JR Liddell… - Journal of …, 2023 - Wiley Online Library
Since the first description of Parkinson's disease (PD) over two centuries ago, the
recognition of rare types of atypical parkinsonism has introduced a spectrum of related PD …

(BIO) ANALYTICAL APPROACHES FOR INVESTIGATING THE ROLE OF SELENIUM IN PREVENTING NEUROLOGICAL DISORDERS AND NEUROTOXICITY …

B Gómez-Gómez, T Fernández-Bautista… - TrAC Trends in Analytical …, 2024 - Elsevier
There is increasing evidence that dysfunction of essential metal (Cu, Zn, Fe, Mn)
homeostasis can lead to the appearance of several NDs. Other neurotoxic environmental …

Exploration and application of chemico-biology detection methods and patterns for factors inducing protein misfolding

X Gao, J Zhai, X He, W Ding, B Shen - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Protein misfolding and aggregation are the leading cause of many diseases, including
neuron degenerative diseases, cardiovascular diseases, and cancers. However, the …

Emerging concepts towards a translational framework in Alzheimer's disease

D Cozachenco, ER Zimmer, MV Lourenco - Neuroscience & Biobehavioral …, 2023 - Elsevier
Over the past decades, significant efforts have been made to understand the precise
mechanisms underlying the pathogenesis of Alzheimer's disease (AD), the most common …

A Comprehensive Review on the Roles of Metals Mediating Insect–Microbial Pathogen Interactions

S Khan, M Lang - Metabolites, 2023 - mdpi.com
Insects and microbial pathogens are ubiquitous and play significant roles in various
biological processes, while microbial pathogens are microscopic organisms that can cause …

Native Cryo-Correlative Light and Synchrotron X-ray Fluorescence Imaging of Proteins and Essential Metals in Subcellular Neuronal Compartments

R Ortega, M Fernández-Monreal, N Pied… - … & Biomedical Imaging, 2024 - ACS Publications
Essential metals such as iron, copper, and zinc are required for a wide variety of biological
processes. For example, they act as cofactors in many proteins, conferring enzymatic activity …

Correlation of metal ions with specific brain region volumes in neurodegenerative diseases

IM Melek, B Kuş, Z Kaptan… - Turkish Journal of …, 2023 - journals.tubitak.gov.tr
Background/aim: There are reports stating that deteriorations in metal homeostasis in
neurodegenerative diseases promote abnormal protein accumulation. In this study, the …

Grape extract and resveratrol mitigate sleep fragmentation, Aβ accumulation, and abnormal neuronal excitability in a Drosophila model of Alzheimer's disease

Z Yu, Y Xu, Y Ping - bioRxiv, 2024 - biorxiv.org
Consumption of red wine and grape extracts may offer a range of health benefits, largely
attributable to the grapes' rich content of vitamins, fiber, and antioxidant compounds, such as …