Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19?

H Shakoor, J Feehan, AS Al Dhaheri, HI Ali, C Platat… - Maturitas, 2021 - Elsevier
The world is currently in the grips of the coronavirus disease (COVID-19) pandemic, caused
by the SARS-CoV-2 virus, which has mutated to allow human-to-human spread. Infection …

A review of micronutrients and the immune system–working in harmony to reduce the risk of infection

AF Gombart, A Pierre, S Maggini - Nutrients, 2020 - mdpi.com
Immune support by micronutrients is historically based on vitamin C deficiency and
supplementation in scurvy in early times. It has since been established that the complex …

Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells

D Chauss, T Freiwald, R McGregor, B Yan, L Wang… - Nature …, 2022 - nature.com
The molecular mechanisms governing orderly shutdown and retraction of CD4+ type 1
helper T (TH1) cell responses remain poorly understood. Here we show that complement …

Vitamin D status in hospitalized patients with SARS-CoV-2 infection

JL Hernández, D Nan… - The Journal of …, 2021 - academic.oup.com
Background The role of vitamin D status in COVID-19 patients is a matter of debate.
Objectives To assess serum 25-hydroxyvitamin D (25OHD) levels in hospitalized patients …

Immunologic effects of vitamin D on human health and disease

N Charoenngam, MF Holick - Nutrients, 2020 - mdpi.com
Vitamin D is responsible for regulation of calcium and phosphate metabolism and
maintaining a healthy mineralized skeleton. It is also known as an immunomodulatory …

An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

[HTML][HTML] Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths

WB Grant, H Lahore, SL McDonnell, CA Baggerly… - Nutrients, 2020 - mdpi.com
The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce
the risk of infection and death in addition to quarantines are desperately needed. This article …

[HTML][HTML] Vitamin D's effect on immune function

PJ Martens, C Gysemans, A Verstuyf, C Mathieu - Nutrients, 2020 - mdpi.com
Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

Lymphopenia in COVID‐19: Therapeutic opportunities

N Fathi, N Rezaei - Cell biology international, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is uncontrollably spread
all over the world. The host immune responses strongly try to confront it with all the potential …

Vitamin D and immune regulation: antibacterial, antiviral, anti-inflammatory

EL Bishop, A Ismailova, S Dimeloe… - Journal of Bone and …, 2021 - academic.oup.com
Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …