2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …

F Mach, C Baigent, AL Catapano… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

[HTML][HTML] Pathophysiology of non alcoholic fatty liver disease

S Petta, A Gastaldelli, E Rebelos, E Bugianesi… - International journal of …, 2016 - mdpi.com
The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style
and inflammation, which have a major impact on the severity of the clinicopathologic …

Role of inflammation in diabetic nephropathy

O Lenz, A Fornoni, A Ijaz, T Tejada - Current diabetes reviews, 2008 - ingentaconnect.com
Diabetic nephropathy (DN) is the leading cause of end stage renal disease (ESRD).
Although the pathogenesis of DN is multifactorial, local inflammatory stress may result from …

Systemic and renal lipids in kidney disease development and progression

P Wahl, GM Ducasa, A Fornoni - American Journal of …, 2016 - journals.physiology.org
Altered lipid metabolism characterizes proteinuria and chronic kidney diseases. While it is
thought that dyslipidemia is a consequence of kidney disease, a large body of clinical and …

Managing dyslipidemia in chronic kidney disease

CR Harper, TA Jacobson - Journal of the American College of Cardiology, 2008 - jacc.org
The incidence of chronic kidney disease (CKD) in the US continues to increase, and now
over 10% of the US population has some form of CKD. Although some patients with CKD will …

Statins and multiple noncardiovascular outcomes: umbrella review of meta-analyses of observational studies and randomized controlled trials

Y He, X Li, D Gasevic, E Brunt, F McLachlan… - Annals of internal …, 2018 - acpjournals.org
Background: Many effects of statins on non–cardiovascular disease (non-CVD) outcomes
have been reported. Purpose: To evaluate the quantity, validity, and credibility of evidence …

Nephropathy in diabetes

B Satirapoj - Diabetes: An Old Disease, a New Insight, 2013 - Springer
The most common cause of end stage renal disease (ESRD) requiring dialysis is diabetes.
Both environmental and genetic factors have been postulated as the risk factors of Diabetic …

Lipid biology of the podocyte—new perspectives offer new opportunities

A Fornoni, S Merscher, JB Kopp - Nature Reviews Nephrology, 2014 - nature.com
In the past 15 years, major advances have been made in understanding the role of lipids in
podocyte biology. First, susceptibility to focal segmental glomerulosclerosis (FSGS) and …

Treatment targets in renal fibrosis

P Boor, K Šebeková, T Ostendorf… - Nephrology Dialysis …, 2007 - academic.oup.com
Renal fibrosis is the principal process underlying the progression of chronic kidney disease
(CKD) to endstage renal disease (ESRD). It is a relatively uniform response involving …

[HTML][HTML] Statins in Chronic Kidney Disease—Effects on Atherosclerosis and Cellular Senescence

P Fularski, J Krzemińska, N Lewandowska… - Cells, 2023 - mdpi.com
Chronic kidney disease (CKD) is a serious health problem that can affect various systems in
the human body. Renal failure promotes mechanisms of premature cellular aging and also …