Cardiovascular disease in patients with diabetic nephropathy

Y Aso - Current Molecular Medicine, 2008 - ingentaconnect.com
Diabetic nephropathy, which represents a major form of chronic kidney disease (CKD), is a
leading cause of end-stage renal disease worldwide, and is also a risk factor for …

Comparative efficacy and adverse effects of the addition of ezetimibe to statin versus statin titration in chronic kidney disease patients

H Suzuki, Y Watanabe, H Kumagai… - Therapeutic advances …, 2013 - journals.sagepub.com
Background and Objectives: The recent SHARP trial clearly demonstrated that a reduction in
low-density lipoprotein (LDL) cholesterol with a daily regimen of simvastatin plus ezetimibe …

Lipid deposition in kidney diseases: interplay among redox, lipid mediators, and renal impairment

H Su, C Wan, CT Lei, CY Zhang, C Ye… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: The relationship between lipid disturbances and renal diseases has been
studied for several decades, and it is well recognized that when the balance of renal lipid …

Potentials of Natural Antioxidants in Reducing Inflammation and Oxidative Stress in Chronic Kidney Disease

OYA Lee, ANN Wong, CY Ho, KW Tse, AZ Chan… - Antioxidants, 2024 - mdpi.com
Chronic kidney disease (CKD) presents a substantial global public health challenge, with
high morbidity and mortality. CKD patients often experience dyslipidaemia and poor …

Re-thinking diabetic nephropathy: Microalbuminuria is just a piece of the diagnostic puzzle

DC Ceccarelli, R Paleari, B Solerte, A Mosca - Clinica Chimica Acta, 2022 - Elsevier
The decline of the estimated glomerular filtration rate (eGFR) and the presence of
albuminuria are the typical hallmarks of kidney disease arising as one of the most frequent …

Atorvastatin reduces proteinuria in non‐diabetic chronic kidney disease patients partly via lowering serum levels of advanced glycation end products (AGEs)

T Nakamura, E Sato, N Fujiwara… - Oxidative Medicine …, 2010 - Wiley Online Library
There is accumulating evidence that advanced glycation end products (AGEs) play a role in
the development and progression of chronic kidney disease (CKD). We have previously …

Simvastatin protects bladder and renal functions following spinal cord injury in rats

A Shunmugavel, M Khan, PC Te Chou… - Journal of …, 2010 - Springer
Background Urinary bladder and renal dysfunction are secondary events associated with
spinal cord injury (SCI) in humans. These secondary events not only compromise quality of …

Atorvastatin affects the tissue concentration of hydrogen sulfide in mouse kidneys and other organs

B Wiliński, J Wiliński, E Somogyi, J Piotrowska… - Pharmacological …, 2011 - Springer
Hydrogen sulfide (H 2 S) is a crucial co-modulator of cardiovascular, nervous, digestive and
excretory systems function. The pleio-tropic action of atorvastatin exceeds simple 3-hydroxy …

Aminopeptidase activities, oxidative stress and renal function in Crotalus durissus terrificus envenomation in mice

SC Yamasaki, JS Villarroel, JM Barone… - Toxicon, 2008 - Elsevier
Acute renal failure is a serious condition of Crotalus bites, which could be treated with
statins. The effects of Crotalus durissus terrificus venom (vCdt) and simvastatin on renal …

Efficacy and safety of Monascus purpureus Went rice in subjects with secondary hyperlipidemia

O Gheith, H Sheashaa, M Abdelsalam, Z Shoeir… - Clinical and …, 2008 - Springer
Background/aims Nephrotic dyslipidemia is a risk factor for the development of systemic
atherosclerosis; it may also aggravate glomerulosclerosis and enhance the progression of …