The development of combination immunotherapy based on the mediation of regulatory
mechanisms of the tumor immune microenvironment (TIME) is promising. However, a deep …

Chemo-radiotherapy and systemic therapies have proven satisfactory outcomes as standard
treatments for various thoracic malignancies; however, adverse pulmonary effects, like …

Radiation pneumonitis (RP) and radiation fibrosis (RF) are two dose-limiting toxicities of
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …

Abstract Purpose “FLASH” radiotherapy (RT) is a potential paradigm-changing RT
technology with marked tumor killing and normal tissue sparing. However, the mechanism of …

Radiation therapy is one of the most common treatment strategies for thorax malignancies.
One of the considerable limitations of this therapy is its toxicity to normal tissue. The lung is …

Purpose The purpose of this study was to explore gains in predictive model performance for
radiation pneumonitis (RP) using pretreatment CT radiomics features extracted from the …

Purpose To predict radiation pneumonitis (RP) grade 2 or worse after lung stereotactic body
radiation therapy (SBRT) using dose‐based radiomic (dosiomic) features. Methods This …

Purpose Radiation pneumonitis (RP) is one of the common side effects of radiation therapy
in the thoracic region. Radiomics and dosiomics quantify information implicit within medical …

Purpose Stereotactic body radiation therapy (SBRT) has become the standard of care for
inoperable early-stage non-small cell lung cancer and is often used for recurrent lung …

Radiotherapy plays an important role in the treatment of localized primary malignancies
involving the chest wall or intrathoracic malignancies. Secondary effects of radiotherapy on …