The spectrum of fungi that infects humans

JR Köhler, A Casadevall… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Few among the millions of fungal species fulfill four basic conditions necessary to infect
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …

Membrane vesicle release in bacteria, eukaryotes, and archaea: a conserved yet underappreciated aspect of microbial life

BL Deatherage, BT Cookson - Infection and immunity, 2012 - Am Soc Microbiol
Interaction of microbes with their environment depends on features of the dynamic microbial
surface throughout cell growth and division. Surface modifications, whether used to acquire …

[HTML][HTML] Exosomes and other extracellular vesicles: the new communicators in parasite infections

G Coakley, RM Maizels, AH Buck - Trends in parasitology, 2015 - cell.com
Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. In addition to their …

[HTML][HTML] Fungal melanin: what do we know about structure?

JD Nosanchuk, RE Stark, A Casadevall - Frontiers in microbiology, 2015 - frontiersin.org
The production of melanin significantly enhances the virulence of many important human
pathogenic fungi. Despite fungal melanin's importance in human disease, as well as …

[HTML][HTML] Extracellular vesicles in fungi: past, present, and future perspectives

J Rizzo, ML Rodrigues, G Janbon - Frontiers in cellular and infection …, 2020 - frontiersin.org
Extracellular vesicles (EVs) have garnered much interest in the cell biology and biomedical
research fields. Many studies have reported the existence of EVs in all types of living cells …

Proteomics, transcriptomics and lipidomics of exosomes and ectosomes

DS Choi, DK Kim, YK Kim, YS Gho - Proteomics, 2013 - Wiley Online Library
Mammalian cells secrete two types of extracellular vesicles either constitutively or in a
regulated manner: exosomes (50–100 nm in diameter) released from the intracellular …

Fungi that infect humans

JR Köhler, B Hube, R Puccia, A Casadevall… - Microbiology …, 2017 - Am Soc Microbiol
Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

[HTML][HTML] Biofortification of major crop plants with iron and zinc-achievements and future directions

JCR Stangoulis, M Knez - Plant and Soil, 2022 - Springer
Biofortification is a long-term strategy of delivering more iron (Fe) and zinc (Zn) to those most
in need. Plant breeding programs within the CGIAR and NARS have made major advances …

[HTML][HTML] Coordination of fungal biofilm development by extracellular vesicle cargo

R Zarnowski, A Noll, MG Chevrette, H Sanchez… - Nature …, 2021 - nature.com
The fungal pathogen Candida albicans can form biofilms that protect it from drugs and the
immune system. The biofilm cells release extracellular vesicles (EVs) that promote …

Functions of fungal melanin beyond virulence

RJB Cordero, A Casadevall - Fungal Biology Reviews, 2017 - Elsevier
Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in
microbial pathogenesis is well established; however, these complex biomolecules also …