Cardiac ionic currents and acute ischemia: from channels to arrhythmias

E Carmeliet - Physiological reviews, 1999 - journals.physiology.org
The aim of this review is to provide basic information on the electrophysiological changes
during acute ischemia and reperfusion from the level of ion channels up to the level of …

Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise

OM Sejersted, G Sjøgaard - Physiological reviews, 2000 - journals.physiology.org
Since it became clear that K+ shifts with exercise are extensive and can cause more than a
doubling of the extracellular [K+]([K+] s) as reviewed here, it has been suggested that these …

Resting membrane potential, extracellular potassium activity, and intracellular sodium activity during acute global ischemia in isolated perfused guinea pig hearts.

AG Kléber - Circulation research, 1983 - Am Heart Assoc
Transmembrane potentials, extracellular potassium activity, and intracellular sodium activity
were determined during acute global ischemia in Langendorff perfused guinea pig …

Neutral carrier based ion-selective electrodes

D Ammann, WE Morf, P Anker, PC Meier… - Ion-selective electrode …, 1983 - Elsevier
Ion carriers (a class of ionophores] are lipophilic complexing agents that have the capability
to reversibly bind ions and to transport these across organic membranes by carrier …

Effect of acute coronary artery occlusion on local myocardial extracellular K+ activity in swine.

JL Hill, LS Gettes - Circulation, 1980 - Am Heart Assoc
We studied the time course, magnitude and homogeneity of the change in extracellular
myocardial potassium activity after acute ligation of the left anterior descending coronary …

Distribution of extracellular potassium and its relation to electrophysiologic changes during acute myocardial ischemia in the isolated perfused porcine heart.

R Coronel, JW Fiolet, FJ Wilms-Schopman… - Circulation, 1988 - Am Heart Assoc
An experimental approach is described to quantitate inhomogeneity in extracellular K
concentration ([K+] out) in the presence of ischemia and to relate this inhomogeneity to the …

Myocardial extracellular K+ and H+ increase and noradrenaline release as possible cause of early arrhythmias following acute coronary artery occlusion in pigs

C Franz, L Bös, R Bissig, R Lang, M Schramm - Journal of molecular and …, 1980 - Elsevier
In 22 young domestic pigs, after thoracotomy, the distal half of the ramus descendens
anterior of the left coronary artery was occluded. This caused an ischemia affecting about …

Interaction of acidosis and increased extracellular potassium on action potential characteristics and conduction in guinea pig ventricular muscle.

Y Kagiyama, JL Hill, LS Gettes - Circulation research, 1982 - Am Heart Assoc
We studied the individual and combined effects of extracellular acidosis and increases in
extracellular potassium on action potential characteristics and conduction in order to gain a …

Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel.

AA Wilde, D Escande, CA Schumacher… - Circulation …, 1990 - Am Heart Assoc
We investigated the contribution of opening of the ATP-sensitive K+ channel to extracellular
accumulation of K+ during ischemia with the use of glibenclamide, a specific blocker of this …

Extracellular potassium accumulation in acute myocardial ischemia

AG Kléber - Journal of molecular and cellular cardiology, 1984 - Elsevier
In acute reversible myocardial ischemia extracellular potassium activity rises 4 to 5 fold
within 10 to 15 min after interruption of coronary perfusion. The underlying net cellular K+ …