Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Gut microbiota in COVID-19: new insights from inside

B Zhou, X Pang, J Wu, T Liu, B Wang, H Cao - Gut microbes, 2023 - Taylor & Francis
The epidemic of coronavirus disease-19 (COVID-19) has grown to be a global health threat.
Gastrointestinal symptoms are thought to be common clinical manifestations apart from a …

The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways

H Kang, W Zhang, J Jing, D Huang, L Zhang… - Journal of Hazardous …, 2023 - Elsevier
The production of plastic is still increasing globally, which has led to an increasing number
of plastic particles in the environment. Nanoplastics (NPs) can penetrate the blood-brain …

Inhibitory effect of Dendrobium officinale polysaccharide on oxidative damage of glial cells in aging mice by regulating gut microbiota

L Xu, X Zeng, Y Liu, Z Wu, X Zheng, X Zhang - International Journal of …, 2023 - Elsevier
Polysaccharides extracted from Dendrobium officinale have various physiological effects. In
this study, we used D-galactose-induced senescent mice as an animal model to investigate …

Neuroprotective effects of polysaccharide from Sparassis crispa on Alzheimer's disease-like mice: Involvement of microbiota-gut-brain axis

W Zhang, Y Guo, Y Cheng, W Yao, H Qian - International journal of …, 2023 - Elsevier
Alzheimer's disease (AD) is an irreversible neurodegenerative disease that may cause
neurotoxicity and imbalance in gut microbiota. A polysaccharide derived from Sparassis …

Effect of Dendrobium officinale polysaccharides on central nervous system disease: Based on gut microbiota

L Xu, X Zeng, Y Liu, Z Wu, X Zheng, X Zhang - International Journal of …, 2023 - Elsevier
Dendrobium officinale has anti-inflammatory effects and is one of the well-known functional
foods. Dendrobium officinale polysaccharide (DOP) can reduce intestinal barrier disruption …

Neuroprotection of food bioactives in neurodegenerative diseases: role of the gut microbiota and innate immune receptors

Y Sun, CT Ho, X Zhang - Journal of agricultural and food chemistry, 2023 - ACS Publications
Gut-brain connections may be mediated by an assortment of microbial molecules, which can
subsequently traverse intestinal and blood-brain barriers and impact neurological function …

The linkage of gut microbiota and the property theory of traditional Chinese medicine (TCM): cold-natured and sweet-flavored TCMs as an example

Y Yang, C Wu - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance The property theory of traditional Chinese medicine (TCM)
is a unique medical theory based on an extensive clinical practice for thousands of years …

Alleviation of Alcoholic Fatty Liver by Dendrobium officinale Flower Extracts due to Regulation of Gut Microbiota and Short-Chain Fatty Acids in Mice Exposed to …

J Zhang, J Fan, H Luo, Z Liang, Y Guan, X Lei, N Bo… - Foods, 2023 - mdpi.com
Alcoholic fatty liver disease (AFLD) is caused by long-term heavy alcohol consumption;
therefore, useful and practical methods for the prevention of AFLD are urgently needed. The …

[HTML][HTML] Oolong tea polyphenols affect the inflammatory response to improve cognitive function by regulating gut microbiota

Z Song, X Zhang, M Hong, Z Wu, S Luo… - Journal of Functional …, 2023 - Elsevier
Oolong tea polyphenols (OTP) has received increasing attention for their ability to reduce
cognitive dysfunction by modulating the gut microbiota and related metabolites. In our study …