Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Hypoxic ischemic brain injury (HIBI) after cardiac arrest (CA) is a leading cause of mortality
and long-term neurologic disability in survivors. The pathophysiology of HIBI encompasses …

Background: Associations of higher indoor carbon dioxide (CO2) concentrations with
impaired work performance, increased health symptoms, and poorer perceived air quality …

Successful resuscitation from cardiac arrest results in a post–cardiac arrest syndrome, which
can evolve in the days to weeks after return of sustained circulation. The components of post …

Cerebral blood flow (CBF) and its distribution are highly sensitive to changes in the partial
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …

Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …

Early brain development, from the embryonic period to infancy, is characterized by rapid
structural and functional changes. These changes can be studied using structural and …

Background and aim COVID-19 pandemic has resulted in an unprecedented increased
usage of Personal protective equipment (PPE) by healthcare-workers. PPE usage causes …

Cerebrovascular reactivity (CVR) is defined as the ability of vessels to alter their caliber in
response to vasoactive factors, by means of dilating or constricting, in order to increase or …

Background—Partial pressure of arterial CO2 (Paco2) is a regulator of cerebral blood flow
after brain injury. Recent guidelines for the management of cardiac arrest recommend …