Until recently, the mammalian tachykinins included substance P, neurokinin A and
neurokinin B. Following the discovery of the fourth member of this family, hemokinin 1, a …

The substance P/neurokinin-1 receptor system has been implicated in tumor cell
proliferation. Neurokinin-1 receptor has been identified in different solid tumors but not …

Background Tachykinins (TK s) are a family of endogenous peptides widely expressed in
the central and in the peripheral nervous systems as well as in the gastrointestinal (GI) tract …

The role of substance P (SP) in physiological haematopoiesis is well established. However,
it also seems to be important in the neoplastic transformation of bone marrow, leading to the …

BACKGROUND Tachykinins and tachykinin receptors are widely distributed in the male
reproductive tract and appear to be involved in reproduction. However, the function and …

purpose. Pterygium is a prevalent ocular surface disorder thought to be triggered by chronic
ultraviolet damage to the limbus. One of the enigmatic features of pterygium is its wing-like …

Background We examined the presence and function of tachykinins and the tachykinin-
degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa …

In mammals, neurokinin B (NKB) is a short peptide encoded by the gene tac3. It is involved
in the brain control of reproduction by stimulating gonadotropin-releasing hormone (GnRH) …

The aim of this study was to analyze the function and expression of tachykinins, tachykinin
receptors, and neprilysin (NEP) in the mouse uterus. A previous study showed that the …

Pruritus is an unpleasant sensation of the skin, which triggers a desire to scratch or rub. The
chronic form (≥ 6 weeks' duration) often occurs as a side effect of many diseases and is …