[图书][B] N-linked glycosylation of the neurokinin 1 receptor: Functional consequences of glycosylation alterations
MF Tansky - 2006 - search.proquest.com
Abstract Neurokinin-1 receptor (NK1R), a G-protein coupled receptor involved in diverse
functions including pain and inflammation, has two putative N-linked glycosylation sites, at …
functions including pain and inflammation, has two putative N-linked glycosylation sites, at …
[PDF][PDF] Neurokinin-1 receptor antagonists: A comprehensive patent survey
VL Korlipara - Citeseer
What the reader will gain: Chemically diverse non-peptide NK1 receptor antagonists have
been identified since the discovery of CP-96,345 by Pfizer in 1991. Representative …
been identified since the discovery of CP-96,345 by Pfizer in 1991. Representative …
NK-1 Antagonists
S Ständer - Pruritus, 2016 - Springer
The skin contains a vital mediator of pro-inflammatory mechanisms called substance P (SP).
SP targets various cells associated with the cutaneous induction of pruritus, for example …
SP targets various cells associated with the cutaneous induction of pruritus, for example …
NK-1 Antagonists
P Substance - Pruritus, 2016 - books.google.com
Substance P (SP) is not only an important mediator for neuroimmune mechanisms, but a
causal agent involved in maintaining pruritus in the central nervous system (CNS) and skin …
causal agent involved in maintaining pruritus in the central nervous system (CNS) and skin …
[PDF][PDF] Nuevos fármacos en hemopatía aguda maligna: antagonistas del receptor NK-1 en leucemia aguda mieloblástica
A Molinos Quintana - 2016 - idus.us.es
Hay momentos en la vida en los que decidir marcar nuevos retos personales y
profesionales pueden hacer de ti una persona nueva, más valiente, un constructor de la …
profesionales pueden hacer de ti una persona nueva, más valiente, un constructor de la …
[HTML][HTML] Therapeutic Potential of 17β Estradiol with Tachykinin Neuropeptide NKB and Aβ (25-35) on Na+-K+ ATPase Activity in Aging Female Rat Brain
The Na+-K+ ATPase is an enzyme responsible for the active transport of Na+ and K+ in most
eukaryotic cells. The aim of the present study was to determine the effect of Tachykinin …
eukaryotic cells. The aim of the present study was to determine the effect of Tachykinin …
[PDF][PDF] Experimental and Clinical Research
R Jha, AAMSP Najma, Z Baquer, SM Cowsik - Am J Exp Clin Res, 2014 - academia.edu
Changes in the fluidity of membrane lipids are known to occur during aging and by lipid
peroxidation. It is well documented that the fluidity state of the lipid phase in a membrane is …
peroxidation. It is well documented that the fluidity state of the lipid phase in a membrane is …
[PDF][PDF] Elucidating mechanisms by which substance P in the RVM contributes to the maintenance of pain following inflammatory injury
UP Maduka - 2013 - iro.uiowa.edu
Chronic pain is a major healthcare concern that directly affects over one hundred million
people in the United States alone. While current treatment options like opioids and NSAIDs …
people in the United States alone. While current treatment options like opioids and NSAIDs …
[HTML][HTML] Effects of tachykinin neuropeptide NKB and Aβ (25-35) on antioxidant enzymes status in 17β estradiol treated aging female rats
J Rashmi, M Abbas Ali, P Shivani, B Najma Z… - Advances in Aging …, 2013 - scirp.org
Aging is the leading risk factor for neurodegenerative diseases and oxidative stress involved
in the pathophysiology of these diseases. These changes increase during menopausal …
in the pathophysiology of these diseases. These changes increase during menopausal …
[HTML][HTML] Neuroprotective role of 17β estradiol with tachykinin neuropeptide NKB and Aβ (25 - 35) in aging female rat brain
J Rashmi, M Abbas Ali, P Shivani, B Najma Z… - Advances in Aging …, 2013 - scirp.org
The brain experiences structural, molecular and functional alterations during aging. In aging
brain tissue, the oxidative stress increases due to decreased activity of antioxidant enzymes …
brain tissue, the oxidative stress increases due to decreased activity of antioxidant enzymes …