Stress, hormonal changes, alcohol, food constituents and drugs: factors that advance the incidence of tobacco smoke-related cancer?

E Maser - Trends in pharmacological sciences, 1997 - cell.com
The genotoxicity of the most potent carcinogen in cigarette smoke [4-(methylnitrosamino)-1-
(3-pyridyl)-1-butanone (NNK)] is dependent on the relationship between its activation by …

The tissue distribution and the tissue specificity of bioactivation of some tobacco-specific and some other N-nitrosamines

H Tjälve - Critical reviews in toxicology, 1991 - Taylor & Francis
Several N-nitrosamines are present in tobacco and tobacco smoke due to nitrosation of
amines during the processing and burning of the tobacco. N-Nitrosamine-formation may …

Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man

E Richter, J Engl, S Friesenegger… - Chemical research in …, 2009 - ACS Publications
Exposure to the tobacco-specific N-nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK) is considered to be an important etiological risk factor for lung cancer in …

Biotransformation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in freshly isolated human lung cells

GBJ Smith, A Castonguay, PJ Donnelly… - …, 1999 - academic.oup.com
Metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK) was characterized in human lung cells isolated from peripheral lung …

Effect of nicotine, cotinine and phenethyl isothiocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in the Syrian golden hamster

E Richter, AR Tricker - Toxicology, 2002 - Elsevier
The effect of nicotine, cotinine and phenethyl isothiocyanate (PEITC) on metabolism of the
tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) was …

[引用][C] Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines

SS Hecht - Chemical research in toxicology, 1998 - experts.umn.edu
Biochemistry, biology, and carcinogenicity of tobacco-specific N- nitrosamines — Experts@Minnesota
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[引用][C] HILIC-MS/MS 测定家兔血液中的NNK 及其7 种代谢物

郎海磊, 王昇, 赵贝贝, 王磊, 洪广峰, 张建勋 - 烟草科技, 2013

[引用][C] Isolation of nonciliated bronchiolar (Clara) epithelial cells from mouse lung

AM Malkinson, FB Miley, CH Chichester… - In Vitro Biological …, 1993 - Elsevier