The roles of acidifiers in polyvinylpyrrolidone-based solid dispersions and physical mixtures
were originally investigated on dissolution rate of drug, acidifier release, structural …

The aims of this study are to increase and explain the mechanism of dissolution
enhancement of isradipine using the sonoprecipitation method for stable nanosuspensions …

Poorly water-soluble drug with a short half-life such as isradipine (IDP) offer challenges in
the controlled release formulation because of low dissolution rate and poor bioavailability …

Isradipine (ID), is an antihypertensive drug, having low oral bioavailability (15–24%) due to
poor aqueous solubility (0.01 mg/mL) and also hepatic first-pass metabolism. Among …

Exposure to chronic and unpredictable stressors can precipitate mood-related disorders in
humans, particularly in individuals with pre-existing mental health challenges. L-type …

The content of this investigation was to study the influence of β-cyclodextrin and hydroxy
propyl-β-cyclodextrin complexation on enhancement of solubility and dissolution rate of …

Inclusion complexes using β-cyclodextrin were manufactured by solvent evaporation
method. Then, sustained release (SR) hydroxypropylmethylcellulose (HPMC) matrix tablets …

Tóm tắt Mục tiêu: Làm tăng tốc độ hòa tan của thuốc khó tan isradipine (IS) bằng hệ phân
tán rắn với polyethylene glycol 6000 (PEG 6000) và nghiên cứu giải thích cơ chế làm tăng …

Antihypertensive treatment is usually very effective in lowering blood pressure to within
normal limits. However, in some individuals, blood pressure remains elevated despite being …

The type of care a preterm baby receives within the first few hours of life can have a
significant impact on their long-term outcome. The phrase “golden hour,” first used in trauma …