Lipopolysaccharide (LPS), a key component of the outer membrane in Gram-negative
bacteria (GNB), is widely recognized for its crucial role in mammalian innate immunity and …

Cancer immunotherapy is a novel pillar of cancer treatment that harnesses the immune
system to fight tumors and generally results in robust antitumor immunity. Although …

Caspase-5 is a protease that induces inflammation in response to lipopolysaccharide (LPS),
a component of the cell envelope of Gram-negative bacteria. The expression level of the …

Gasdermins are membrane pore–forming proteins that cause pyroptosis, an inflammatory
cell death in which cells burst and release cytokines, chemokines, and other host alarm …

Bacterial lipopolysaccharide (LPS) is implicated in disrupting the blood-brain barrier (BBB).
In a recent issue of Nature, Wei et al. now show that LPS activates the inflammatory …

Caspases are a family of cysteine proteases that act as molecular scissors to cleave
substrates and regulate biological processes such as programmed cell death and …