Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

Context-specific signaling is a prevalent theme in cancer biology wherein individual
molecules and pathways can have multiple or even opposite effects depending on the tumor …

Background & Aims Oxidative stress-mediated ferroptosis and macrophage-related
inflammation play an important role in various liver diseases. Here, we explored if and how …

Alternative splicing (AS) is a post-transcriptional regulation that leads to the complexity of the
transcriptome. Despite the growing importance of AS in cancer research, the role of AS has …

The mitogen-activated protein kinase (MAPK) pathways are ubiquitous in cellular signaling
and are essential for proper biological functions. Disruptions in this signaling axis can lead …

The discovery of Helicobacter pylori (Hp) infection of gastric mucosa leading to active
chronic gastritis, gastroduodenal ulcers, and MALT lymphoma laid the groundwork for …

Background: There are 200-600 million betel quid (BQ) chewers in the world. BQ increases
oral cancer risk. Matrix metalloproteinase-9 (MMP-9) is responsible for matrix degradation …

Surgical resection, the cornerstone of curative intent treatment for gastric adenocarcinoma,
is associated with a high rate of infection-related post-operative complications, leading to an …

Hypothemycin, an epoxide derivative of (5 Z)-7-oxozeaenol, was used in the semisynthesis
of a series of C8–C9 diol derivatives, with many inhibiting TAK1 at submicromolar …

Gastric cancer (GC) is the most frequent digestive system malignant tumour and the second
most common cause of cancer death globally. Cancer stem cell (CSC) is a small percentage …