RNAi machinery regulates nutrient metabolism and fluconazole resistance in the pathogenic fungus Cryptococcus deneoformans

X Ma, C Li, L Ma, X Zhao, Y Liu, X Hao… - Medical …, 2023 - academic.oup.com
The RNAi machinery has been extensively studied in plant and animal cells for their crucial
roles in the regulation of genome function. However, the potential roles of RNAi in …

Replicative aging remodels the cell wall and is associated with increased intracellular trafficking in human pathogenic yeasts

VKA Silva, S Bhattacharya, NK Oliveira, AG Savitt… - MBio, 2022 - Am Soc Microbiol
Replicative aging is an underexplored field of research in medical mycology. Cryptococcus
neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal …

High-Throughput Yeast Aging Analysis for Cryptococcus (HYAAC) microfluidic device streamlines aging studies in Cryptococcus neoformans

EP Orner, P Zhang, MC Jo, S Bhattacharya… - Communications …, 2019 - nature.com
Cryptococcus neoformans (Cn) is a deadly fungal pathogen responsible for~ 180,000
deaths per year and despite effective antifungals, treatment failure and resistance to …

How Replicative Aging Contributes to Resilience of Cryptococcus neoformans

EP Orner - 2019 - search.proquest.com
Cryptococcus neoformans is a deadly fungal pathogen responsible for killing 15% of AIDS
patients annually and despite having effective antifungals, the rise of antifungal resistance …