Glycosaminoglycan–protein interactions: the first draft of the glycosaminoglycan interactome

SD Vallet, O Clerc… - Journal of Histochemistry …, 2021 - journals.sagepub.com
The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate,
heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides …

Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being

S Wolf, J Becker, Y Tsuge, H Kawaguchi… - Essays in …, 2021 - portlandpress.com
The soil microbe Corynebacterium glutamicum is a leading workhorse in industrial
biotechnology and has become famous for its power to synthetise amino acids and a range …

[HTML][HTML] Hyaluronic acid and Chondroitin sulfate from marine and terrestrial sources: Extraction and purification methods

MM Abdallah, N Fernández, AA Matias… - Carbohydrate …, 2020 - Elsevier
Hyaluronic acid (HA) and chondroitin sulfate (CS) are valuable bioactive polysaccharides
that have been highly used in biomedical and pharmaceutical applications. Extensive …

[HTML][HTML] Glycosaminoglycan-protein interactions and their roles in human disease

D Shi, A Sheng, L Chi - Frontiers in molecular biosciences, 2021 - frontiersin.org
Glycosaminoglycans (GAGs) are a family of linear and negatively charged polysaccharides
that exist ubiquitously on the human cell surface as well as in the extracellular matrix. GAGs …

Heparin: An old drug for new clinical applications

P Wang, L Chi, Z Zhang, H Zhao, F Zhang… - Carbohydrate …, 2022 - Elsevier
Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

[HTML][HTML] Heparan sulfate biosynthesis and sulfation profiles as modulators of cancer signalling and progression

C Marques, CA Reis, RR Vivès, A Magalhães - Frontiers in oncology, 2021 - frontiersin.org
Heparan Sulfate Proteoglycans (HSPGs) are important cell surface and Extracellular Matrix
(ECM) maestros involved in the orchestration of multiple cellular events in physiology and …

Heparan sulfate proteoglycans in viral infection and treatment: a special focus on SARS-CoV-2

V De Pasquale, MS Quiccione, S Tafuri… - International Journal of …, 2021 - mdpi.com
Heparan sulfate proteoglycans (HSPGs) encompass a group of glycoproteins composed of
unbranched negatively charged heparan sulfate (HS) chains covalently attached to a core …

The alterations and roles of glycosaminoglycans in human diseases

Q Wang, L Chi - Polymers, 2022 - mdpi.com
Glycosaminoglycans (GAGs) are a heterogeneous family of linear polysaccharides which
are composed of a repeating disaccharide unit. They are also linked to core proteins to form …

Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions

H Ji, C Hu, X Yang, Y Liu, G Ji, S Ge, X Wang… - … and Targeted Therapy, 2023 - nature.com
Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune
modulation, and secondary dissemination to distant sites through a series of mechanisms …

[HTML][HTML] The role of proteoglycans in cancer metastasis and circulating tumor cell analysis

TD Ahrens, SR Bang-Christensen… - Frontiers in cell and …, 2020 - frontiersin.org
Circulating tumor cells (CTCs) are accessible by liquid biopsies via an easy blood draw.
They represent not only the primary tumor site, but also potential metastatic lesions, and …