Clinicians must be aware of underappreciated burdens faced by children and families with
food allergies. Management involves a partnership between primary and specialty care …

Background. A common feature of most reviews or catalogues of health utilities has been
their focus on adult health states or derivation of values from adult populations. More …

Purpose This study aimed to estimate the cost-effectiveness of exome sequencing (ES) and
genome sequencing (GS) for children. Methods We modeled costs, diagnoses, and quality …

Purpose To systematically investigate the longer-term clinical and health economic impacts
of genomic sequencing for rare-disease diagnoses. Methods We collected information on …

OBJECTIVE: To compare strategies for the timing of delivery in individuals with placenta
previa and ultrasonographic evidence of placenta accreta, and to determine the optimal …

OBJECTIVE The International Association of the Diabetes and Pregnancy Study Groups
(IADPSG) recently recommended new criteria for diagnosing gestational diabetes mellitus …

With the growth in the use of health economic evaluation to inform healthcare resource
allocation decisions, the challenges in applying standard methods to child health have …

Background Allergic asthma is a long-term disorder of the airways resulting from
overexpression of immunoglobulin E (IgE) in response to environmental allergens. Patients …

Background Early peanut introduction (EPI) in the first year of life is associated with reduced
risk of developing peanut allergy in children with either severe eczema and/or egg allergy …

Background Both oral immunotherapy (OIT) and epicutaneous immunotherapy (EPIT) are
emerging potential treatments for peanut allergy. Caregiver goals and expectations of these …