Fungi represent emerging infectious threats to human populations worldwide. Mice and
other laboratory animals have proved invaluable in modeling clinical syndromes associated …

Since its description nearly 130 years ago, hundreds of studies have deepened our
understanding of coccidioidomycosis, also known as valley fever (VF), and provided useful …

Murine infections with most Coccidioides spp. strains are lethal by 3 weeks, limiting the
study of immune responses. Coccidioides posadasii, strain 1038 (Cp1038), while slowly …

Coccidioidomycosis is a potentially life-threatening respiratory disease which is endemic to
the southwestern United States and arid regions of Central and South America. It is …

Coccidioidomycosis is a fungal disease endemic to the southwestern United States, Mexico,
and Central and South America. Prevalence rates are increasing steadily, and new endemic …

Disseminated coccidioidomycosis is a life-threatening infection. In these studies, we
examined protection against systemic murine coccidioidomycosis by vaccination with heat …

Nikkomycin Z (NikZ) is a chitin synthase inhibitor with antifungal efficacy against
Coccidioides spp. and other endemic fungi. Dogs suffer a rate and range of natural …

A new real-time polymerase chain reaction (RT-PCR) assay based on a Coccidioides genus–
specific molecular beacon probe was developed for the detection of coccidioidomycosis and …

Use of the rabbit as disease model has long been hampered by a lack of immunological
assays specific to this species. In the present study we developed a SYBR Green-based …

Coccidioidomycosis is an endemic infection in the Americas caused by the dimorphic fungi
Coccidioides immitis and Coccidioides posadasii. Although the disease occurs in Brazil in …