Ca2+ toxicity and mitochondrial damage in acute pancreatitis: translational overview
Acute pancreatitis (AP) is a leading cause of hospitalization among non-malignant
gastrointestinal disorders. The mortality of severe AP can reach 30–50%, which is most …
gastrointestinal disorders. The mortality of severe AP can reach 30–50%, which is most …
Calcium signalling in salivary gland physiology and dysfunction
IS Ambudkar - The Journal of physiology, 2016 - Wiley Online Library
Studies over the past four decades have established that Ca2+ is a critical factor in control of
salivary gland function and have led to identification of the critical components of this …
salivary gland function and have led to identification of the critical components of this …
[HTML][HTML] Exogenous enzymes and probiotics alter digestion kinetics, volatile fatty acid content and microbial interactions in the gut of Nile tilapia
Sustainable aquafeed production requires fishmeal replacement, leading to an increasing
use of plant-derived ingredients. As a consequence, higher levels of antinutritional …
use of plant-derived ingredients. As a consequence, higher levels of antinutritional …
[HTML][HTML] Finite volume simulation of calcium distribution in a cholangiocyte cell
Cholangiocytes are the cells of the liver having a major role in the conditioning of bile used
in digestion. Other functions of cholangiocytes are in apoptosis and bicarbonate secretion …
in digestion. Other functions of cholangiocytes are in apoptosis and bicarbonate secretion …
[HTML][HTML] Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitis
J Li, R Zhou, J Zhang, ZF Li - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Pancreatitis is an increasingly common and sometimes severe disease that lacks a specific
therapy. The pathogenesis of pancreatitis is still not well understood. Calcium (Ca 2+) is a …
therapy. The pathogenesis of pancreatitis is still not well understood. Calcium (Ca 2+) is a …
[HTML][HTML] Particulate matter 10 exposure affects intestinal functionality in both inflamed 2D intestinal epithelial cell and 3D intestinal organoid models
YS Son, N Son, WD Yu, A Baek, YJ Park… - Frontiers in …, 2023 - frontiersin.org
Background A growing body of evidence suggests that particulate matter (PM10) enters the
gastrointestinal (GI) tract directly, causing the GI epithelial cells to function less efficiently …
gastrointestinal (GI) tract directly, causing the GI epithelial cells to function less efficiently …
Source of dopamine in gastric juice and luminal dopamine‐induced duodenal bicarbonate secretion via apical dopamine D2 receptors
XY Feng, JT Yan, GW Li, JH Liu, RF Fan… - British Journal of …, 2020 - Wiley Online Library
Background and Purpose Dopamine protects the duodenal mucosa. Here we have
investigated the source of dopamine in gastric juice and the mechanism underlying the …
investigated the source of dopamine in gastric juice and the mechanism underlying the …
Molecular mechanisms of caffeine‐mediated intestinal epithelial ion transports
F Zhang, H Wan, X Yang, J He, C Lu… - British Journal of …, 2019 - Wiley Online Library
Background and Purpose As little is known about the effect of caffeine, one of the most
widely consumed substances worldwide, on intestinal function, we aimed to study its action …
widely consumed substances worldwide, on intestinal function, we aimed to study its action …
[HTML][HTML] Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion
Epithelial ion transport is mainly under the control of intracellular cAMP and Ca 2+ signaling.
Although the molecular mechanisms of cAMP-induced epithelial ion secretion are well …
Although the molecular mechanisms of cAMP-induced epithelial ion secretion are well …
[HTML][HTML] Role of serosal TRPV4-constituted SOCE mechanism in secretagogues-stimulated intestinal epithelial anion secretion
Y Cui, F Chu, K Yin, X Chen, H Wan, G Luo… - Frontiers in …, 2021 - frontiersin.org
As little is known about the role of calcium (Ca2+) signaling mediating the small intestinal
epithelial anion secretion, we aimed to study its regulatory role in secretagogue-stimulated …
epithelial anion secretion, we aimed to study its regulatory role in secretagogue-stimulated …