[HTML][HTML] The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease
Aging is a normal physiological process accompanied by cognitive decline. This aging
process has been the primary risk factor for development of aging-related diseases such as …
process has been the primary risk factor for development of aging-related diseases such as …
Neurotrophin signalling: novel insights into mechanisms and pathophysiology
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators
of neuronal survival, growth and differentiation during development. While trophic factors are …
of neuronal survival, growth and differentiation during development. While trophic factors are …
Neurotrophins and their receptors: a convergence point for many signalling pathways
MV Chao - Nature Reviews Neuroscience, 2003 - nature.com
The neurotrophins are a family of proteins that are essential for the development of the
vertebrate nervous system. Each neurotrophin can signal through two different types of cell …
vertebrate nervous system. Each neurotrophin can signal through two different types of cell …
Trk receptors: roles in neuronal signal transduction
EJ Huang, LF Reichardt - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract Trk receptors are a family of three receptor tyrosine kinases, each of which can be
activated by one or more of four neurotrophins—nerve growth factor (NGF), brain-derived …
activated by one or more of four neurotrophins—nerve growth factor (NGF), brain-derived …
Neurotrophin-regulated signalling pathways
LF Reichardt - … Transactions of the Royal Society B …, 2006 - royalsocietypublishing.org
Neurotrophins are a family of closely related proteins that were identified initially as survival
factors for sensory and sympathetic neurons, and have since been shown to control many …
factors for sensory and sympathetic neurons, and have since been shown to control many …
[HTML][HTML] Brain-derived neurotrophic factor
DK Binder, HE Scharfman - Growth factors (Chur, Switzerland), 2004 - ncbi.nlm.nih.gov
Nerve growth factor (NGF) was discovered in the early 1950s due to its trophic (survival-and
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …
Neurotrophic factors: an overview
SD Skaper - Neurotrophic Factors: Methods and Protocols, 2018 - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …
factors for sympathetic and sensory neurons and have since been shown to control a …
The neurotrophin family of neurotrophic factors: an overview
SD Skaper - Neurotrophic factors: Methods and protocols, 2012 - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …
factors for sympathetic and sensory neurons and have since been shown to control a …
Brain‐derived neurotrophic factor and the development of structural neuronal connectivity
S Cohen‐Cory, AH Kidane, NJ Shirkey… - Developmental …, 2010 - Wiley Online Library
During development, neural networks are established in a highly organized manner, which
persists throughout life. Neurotrophins play crucial roles in the developing nervous system …
persists throughout life. Neurotrophins play crucial roles in the developing nervous system …
Sortilin is essential for proNGF-induced neuronal cell death
A Nykjaer, R Lee, KK Teng, P Jansen, P Madsen… - Nature, 2004 - nature.com
Sortilin (∼ 95 kDa) is a member of the recently discovered family of Vps10p-domain
receptors,, and is expressed in a variety of tissues, notably brain, spinal cord and muscle. It …
receptors,, and is expressed in a variety of tissues, notably brain, spinal cord and muscle. It …