Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is
one of the most common single gene disorders found in the developed world. In this fourth …

A randomized double‐blind therapeutic trial of isaxonine was completed over a 2‐year
period for 20 ambulant boys with Duchenne muscular dystrophy aged 5 1/2–10 years. The …

Postnatal development of three hind legs muscles, the soleus, plantaris, and gastrocnemius,
of dystrophic mice (ReJ 129) was investigated with histochemical and morphometric …

Abstract As Michael Brooke so aptly stated at the beginning of this session on phenotypic
monitoring, it is imperative to have a quantifiable test system in place prior to assessing …

A high‐capacity, step‐wise system for drug evaluation in chickens with inherited muscular
dystrophy has been developed. This report details the protocol and presents the first results …

An enzyme that catalyzes the NADPH-dependent reduction of a wide range of aromatic and
hydroxy-aliphatic aldehydes was purified from chicken breast muscle. This enzyme shares …

Abstract Changes in the ultrastructure of the cardiac muscle cells have been followed in
dystrophic mice and hamsters (22–40 weeks of age) and in both species a severe …

Duchenne muscular dystrophy (DMD) is caused by a mutation of a single gene, dystrophin,
and is characterized by a slow progression and the increased turnover of myofiber …