Decades of research have identified genetic factors and biochemical pathways involved in
neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks …

Neurodegeneration leads to the loss of structural and functioning components of neurons
over time. Various studies have related neurodegeneration to a number of degenerative …

In Parkinson's disease (PD) there is a selective degeneration of neuromelanin-containing
neurons, especially substantia nigra dopaminergic neurons. In humans, neuromelanin …

Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases
of the elderly people that have devastating effects in terms of morbidity and mortality. The …

Parkinson's disease (PD) is an aging-related disease and the second most common
neurodegenerative disease after Alzheimer's disease. The main symptoms of PD are …

Protein aggregation within the central nervous system has been recognized as a defining
feature of neurodegenerative diseases since the early 20th century. Since that time, there …

Increased intracellular levels of α-synuclein are implicated in Parkinson's disease and
related disorders and may be caused by alterations in the ubiquitin–proteasome system …

Neuromelanin, a dark brown intracellular pigment, has long been associated with
Parkinson's disease (PD). In PD, neuromelanin‐containing neurons preferentially …

Currently, neurodegenerative diseases are a major cause of disability around the world.
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …

A rich and complex temporal structure of variability in postural sway characterizes healthy
and adaptable postural control. However, neurodegenerative disorders such as Parkinson's …