Melanin pigments of fungi under extreme environmental conditions

NN Gessler, AS Egorova, TA Belozerskaya - Applied Biochemistry and …, 2014 - Springer
Melanin Pigments of Fungi under Extreme Environmental Conditions (Review) Page 1 ISSN
0003 6838, Applied Biochemistry and Microbiology, 2014, Vol. 50, No. 2, pp. 105–113. © …

The role of melanins in melanotic fungi for pathogenesis and environmental survival

HC Eisenman, EM Greer, CW McGrail - Applied microbiology and …, 2020 - Springer
Melanins provide fungi protection from environmental stressors, support their ecological
roles, and can confer virulence in pathogens. While the function, structure, and synthesis of …

[PDF][PDF] Melanin pigments of fungi

TA Belozerskaya, NN Gessler… - Fungal …, 2017 - ndl.ethernet.edu.et
Fungi possess all kinds of melanins found in nature. These pigments are products of
polymerization of phenolic compounds. Phenolic precursors determine the polymerization …

Reciprocal modulation of ammonia and melanin production has implications for cryptococcal virulence

RP Baker, A Casadevall - Nature communications, 2023 - nature.com
The fungus Cryptococcus neoformans is the causative agent of cryptococcosis, a disease
that is uniformly lethal unless treated with antifungal drugs, yet current regimens are …

HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence

F Brandão, SK Esher, KS Ost, K Pianalto, CB Nichols… - Scientific reports, 2018 - nature.com
The human fungal pathogen Cryptococcus neoformans undergoes many phenotypic
changes to promote its survival in specific ecological niches and inside the host. To explore …

Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells

C Chrissian, E Camacho, JE Kelly, H Wang… - Journal of Biological …, 2020 - ASBMB
A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus
neoformans is the production of melanin pigments that are deposited into the cell wall and …

Cryptococcus neoformans melanization incorporates multiple catecholamines to produce polytypic melanin

RP Baker, C Chrissian, RE Stark… - Journal of Biological …, 2022 - ASBMB
Melanin is a major virulence factor in pathogenic fungi that enhances the ability of fungal
cells to resist immune clearance. Cryptococcus neoformans is an important human …

Sporothrix globosa melanin regulates autophagy via the TLR2 signaling pathway in THP-1 macrophages

M Guan, L Yao, Y Zhen, Y Song, X Liu… - PLOS Neglected …, 2023 - journals.plos.org
Melanin, an important virulence factor of pathogenic fungi, has been shown to suppress host
immune responses in multiple ways. Autophagy is a vital cellular mechanism underlying the …

Update on the epidemiology and management of cryptococcal meningitis

A Desalermos, TK Kourkoumpetis… - Expert opinion on …, 2012 - Taylor & Francis
Despite recent improvements in the diagnosis and treatment of cryptococcosis, cryptococcal
meningitis is responsible for> 600,000 deaths/year worldwide. The aim of this work is to …

Inhibitory effects and mechanism of antifungal action of the natural cyclic depsipeptide, aureobasidin A against Cryptococcus neoformans

M Teymuri, M Shams-Ghahfarokhi… - Bioorganic & Medicinal …, 2021 - Elsevier
Cryptococcosis is an opportunistic fungal infection caused mainly by Cryptococcus
neoformans. The aim of the present study was to evaluate the inhibitory effect of …