Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Epileptic seizures vary greatly in clinical phenomenology and can markedly affect the
patient's quality of life. As therapeutic interventions focus on reduction or elimination of …

Epileptic networks are intimately connected with the autonomic nervous system, as
exemplified by a plethora of ictal (during a seizure) autonomic manifestations, including …

Approximately 50 million people worldwide suffer from epilepsy, and approximately 30% to
40% of these persons have seizures that are refractory to treatment with antiepileptic …

Epilepsy affects millions of people worldwide. Approximately one-third have
pharmacoresistant epilepsy, and of these, the majority are not candidates for epilepsy …

Sudden unexpected death in epilepsy (SUDEP) is generally considered to result from a
seizure, typically convulsive and usually but not always occurring during sleep, followed by …

This educational topical review and Task Force report aims to address learning objectives of
the International League Against Epilepsy (ILAE) curriculum. We sought to extract detailed …

Objective: The present study proposes a new epileptic seizure prediction method through
integrating heart rate variability (HRV) analysis and an anomaly monitoring technique …

Worldwide, population aging and unhealthy lifestyles have increased the incidence of high-
risk health conditions such as cardiovascular diseases, sleep apnea, and other conditions …

Vagus nerve stimulation (VNS) is a safe and effective therapy that has been available for
over 20 years for adults and children with drug resistant epilepsy (DRE). Since US Food and …