[HTML][HTML] Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical …
Background Quality assurance (QA) and quality control (QC) are two quality management
processes that are integral to the success of metabolomics including their application for the …
processes that are integral to the success of metabolomics including their application for the …
Quality assurance procedures for mass spectrometry untargeted metabolomics. a review
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …
capabilities for the investigation of health and disease, as well as the wide applicability for …
A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms
H Tsugawa, R Nakabayashi, T Mori, Y Yamada… - Nature …, 2019 - nature.com
We report a computational approach (implemented in MS-DIAL 3.0; http://prime. psc. riken.
jp/) for metabolite structure characterization using fully 13C-labeled and non-labeled plants …
jp/) for metabolite structure characterization using fully 13C-labeled and non-labeled plants …
Current approaches and challenges for the metabolite profiling of complex natural extracts
Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …
research. Obtaining precise information on the chemical composition of complex natural …
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
WB Dunn, D Broadhurst, P Begley, E Zelena… - Nature protocols, 2011 - nature.com
Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
WB Dunn, DI Broadhurst, HJ Atherton… - Chemical society …, 2011 - pubs.rsc.org
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
Mass spectrometric based approaches in urine metabolomics and biomarker discovery
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans
The metabolic investigation of the human population is becoming increasingly important in
the study of health and disease. The phenotypic variation can be investigated through the …
the study of health and disease. The phenotypic variation can be investigated through the …
[HTML][HTML] Mass spectrometry strategies in metabolomics
MS has evolved as a critical component in metabolomics, which seeks to answer biological
questions through large-scale qualitative and quantitative analyses of the metabolome. MS …
questions through large-scale qualitative and quantitative analyses of the metabolome. MS …
New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era
NL Kuehnbaum, P Britz-McKibbin - Chemical reviews, 2013 - ACS Publications
Metabolomics offers a revolutionary framework for phenotyping individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …