Metabolomics offers a revolutionary framework for phenotyping individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …

Metabolomics allows the simultaneous and relative quantification of thousands of different
metabolites within a given sample using sensitive and specific methodologies such as gas …

Two common features of dietary polyphenols have hampered our mechanistic
understanding of their beneficial effects for decades: targeting multiple organs and …

Microplastics are toxic to aquatic organisms. Metabolic disturbances in the liver are highly
correlated with the pathophysiology of diseases and toxicology of contaminants. However …

Abstract Phenotyping of 1,200 'healthy'adults from the UK has been performed through the
investigation of diverse classes of hydrophilic and lipophilic metabolites present in serum by …

Trichuris species are a globally important and prevalent group of intestinal helminth
parasites, in which Trichuris muris (mouse whipworm) is an ideal model for this disease …

This tutorial provides a comprehensive description of the GC-MS-based untargeted
metabolomics workflow including: ethical approval requirement, sample collection and …

Missing values are known to be problematic for the analysis of gas chromatography-mass
spectrometry (GC-MS) metabolomics data. Typically these values cover about 10%–20% of …

Gas chromatography coupled to mass spectrometry is the most frequent tool for
metabolomic profiling of low molecular weight metabolites. Its suitability in health survey is …

Metabolomics represents a global quantitative assessment of metabolites within a biological
system. The metabolic analysis of cell cultures has many potential applications and …