Messenger-RNA-binding proteins and the messages they carry
G Dreyfuss, VN Kim, N Kataoka - Nature reviews Molecular cell biology, 2002 - nature.com
From sites of transcription in the nucleus to the outreaches of the cytoplasm, messenger
RNAs are associated with RNA-binding proteins. These proteins influence pre-mRNA …
RNAs are associated with RNA-binding proteins. These proteins influence pre-mRNA …
Untranslated regions of mRNAs
Gene expression is finely regulated at the post-transcriptional level. Features of the
untranslated regions of mRNAs that control their translation, degradation and localization …
untranslated regions of mRNAs that control their translation, degradation and localization …
Functional diversity of the hnRNPs: past, present and perspectives
SP Han, YH Tang, R Smith - Biochemical Journal, 2010 - portlandpress.com
The hnRNPs (heterogeneous nuclear ribonucleoproteins) are RNA-binding proteins with
important roles in multiple aspects of nucleic acid metabolism, including the packaging of …
important roles in multiple aspects of nucleic acid metabolism, including the packaging of …
Regulation of the expression of inducible nitric oxide synthase
A Pautz, J Art, S Hahn, S Nowag, C Voss, H Kleinert - Nitric oxide, 2010 - Elsevier
Nitric oxide (NO) generated by the inducible isoform of nitric oxide synthase (iNOS) is
involved in complex immunomodulatory and antitumoral mechanisms and has been …
involved in complex immunomodulatory and antitumoral mechanisms and has been …
AU-rich elements and associated factors: are there unifying principles?
C Barreau, L Paillard, HB Osborne - Nucleic acids research, 2005 - academic.oup.com
The control of mRNA stability is an important process that allows cells to not only limit, but
also rapidly adjust, the expression of regulatory factors whose over expression may be …
also rapidly adjust, the expression of regulatory factors whose over expression may be …
The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis
Dysregulated RNA metabolism is emerging as a crucially important mechanism
underpinning the pathogenesis of frontotemporal dementia (FTD) and the clinically …
underpinning the pathogenesis of frontotemporal dementia (FTD) and the clinically …
Thermostability, tunability, and tenacity of RNA as rubbery anionic polymeric materials in nanotechnology and nanomedicine—specific cancer targeting with …
RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures,
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
RNA binding protein regulation and cross-talk in the control of AU-rich mRNA fate
SM García-Mauriño, F Rivero-Rodríguez… - Frontiers in molecular …, 2017 - frontiersin.org
mRNA metabolism is tightly orchestrated by highly-regulated RNA Binding Proteins (RBPs)
that determine mRNA fate, thereby influencing multiple cellular functions across biological …
that determine mRNA fate, thereby influencing multiple cellular functions across biological …
Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1
J Lykke-Andersen, E Wagner - Genes & development, 2005 - genesdev.cshlp.org
In human cells, a critical pathway in gene regulation subjects mRNAs with AU-rich elements
(AREs) to rapid decay by a poorly understood process. AREs have been shown to directly …
(AREs) to rapid decay by a poorly understood process. AREs have been shown to directly …
hnRNP proteins and splicing control
R Martinez-Contreras, P Cloutier, L Shkreta… - Alternative splicing in …, 2007 - Springer
Proteins of the heterogeneous nuclear ribonucleoparticles (hnRNP) family form a structurally
diverse group of RNA binding proteins implicated in various functions in metazoans. Here …
diverse group of RNA binding proteins implicated in various functions in metazoans. Here …