Foot-and-mouth disease virus VP1 degrades YTHDF2 through autophagy to regulate IRF3 activity for viral replication
H Liu, Q Xue, F Yang, W Cao, P Liu, X Liu, Z Zhu… - Autophagy, 2024 - Taylor & Francis
Many viruses, including foot-and-mouth disease virus (FMDV), can promote the degradation
of host proteins through macroautophagy/autophagy, thereby promoting viral replication …
of host proteins through macroautophagy/autophagy, thereby promoting viral replication …
The E3 ligase ASB3 downregulates antiviral innate immunity by targeting MAVS for ubiquitin-proteasomal degradation
M Cheng, Y Lu, J Wang, H Wang, Y Sun… - Cell Death & …, 2024 - nature.com
E3 ubiquitin ligases are very important for regulating antiviral immunity during viral infection.
Here, we discovered that Ankyrin repeat and SOCS box-containing protein 3 (ASB3), an E3 …
Here, we discovered that Ankyrin repeat and SOCS box-containing protein 3 (ASB3), an E3 …
Zinc-finger CCHC-type containing protein 8 promotes RNA virus replication by suppressing the type-I interferon responses
S Tu, J Zou, C Xiong, C Dai, H Sun, D Luo… - Journal of …, 2024 - journals.asm.org
Host cells have evolved an intricate regulatory network to fine tune the type-I interferon
responses. However, the full picture of this regulatory network remains to be depicted. In this …
responses. However, the full picture of this regulatory network remains to be depicted. In this …
Transcriptomic responses to shifts in light and nitrogen in two congeneric diatom species
X Ma, Z Qin, KB Johnson, LH Sweat, S Dai… - Frontiers in …, 2024 - frontiersin.org
Light and nitrogen availability are basic requirements for photosynthesis. Changing in light
intensity and nitrogen concentration may require adaptive physiological and life process …
intensity and nitrogen concentration may require adaptive physiological and life process …
PZR suppresses innate immune response to RNA viral infection by inhibiting MAVS activation in interferon signaling mediated by RIG-I and MDA5
R Deng, L Zhang, S Chen, X Li, B Xue, H Li, Y Xu… - Antiviral Research, 2024 - Elsevier
RNA viral infections seriously endanger human health. Src homology 2 (SH2) domain-
containing protein tyrosine phosphatase 2 (SHP2) suppresses innate immunity against …
containing protein tyrosine phosphatase 2 (SHP2) suppresses innate immunity against …