Ventilator management and respiratory care after cardiac arrest: oxygenation, ventilation, infection, and injury

NJ Johnson, DJ Carlbom, DF Gaieski - Chest, 2018 - Elsevier
Return of spontaneous circulation after cardiac arrest results in a systemic inflammatory
state called the post-cardiac arrest syndrome, which is characterized by oxidative stress …

[HTML][HTML] Targeting two different levels of both arterial carbon dioxide and arterial oxygen after cardiac arrest and resuscitation: a randomised pilot trial

P Jakkula, M Reinikainen, J Hästbacka, P Loisa… - Intensive care …, 2018 - Springer
Purpose We assessed the effects of targeting low-normal or high-normal arterial carbon
dioxide tension (PaCO 2) and normoxia or moderate hyperoxia after out-of-hospital cardiac …

[HTML][HTML] Narrative review of neurologic complications in adults on ECMO: prevalence, risks, outcomes, and prevention strategies

H Zhang, J Xu, X Yang, X Zou, H Shu, Z Liu… - Frontiers in …, 2021 - frontiersin.org
Extracorporeal membrane oxygenation (ECMO), a life-saving technique for patients with
severe respiratory and cardiac diseases, is being increasingly utilized worldwide …

The acute respiratory distress syndrome after out-of-hospital cardiac arrest: Incidence, risk factors, and outcomes

NJ Johnson, E Caldwell, DJ Carlbom, DF Gaieski… - Resuscitation, 2019 - Elsevier
Objective To define the incidence of the acute respiratory distress syndrome (ARDS)
following out-of-hospital cardiac arrest (OHCA) and characterize its impact on outcome …

Association of hypercapnia and hypercapnic acidosis with clinical outcomes in mechanically ventilated patients with cerebral injury

R Tiruvoipati, D Pilcher, J Botha, H Buscher… - JAMA …, 2018 - jamanetwork.com
Importance Clinical studies investigating the effects of hypercapnia and hypercapnic
acidosis in acute cerebral injury are limited. The studies performed so far have mainly …

[HTML][HTML] Association between low pH and unfavorable neurological outcome among out-of-hospital cardiac arrest patients treated by extracorporeal CPR: a …

Y Okada, T Kiguchi, T Irisawa, K Yoshiya… - Journal of Intensive …, 2020 - Springer
Background We aimed to identify the association of pH value in blood gas assessment with
neurological outcome among out-of-hospital cardiac arrest (OHCA) patients treated by …

Association between arterial carbon dioxide tension and clinical outcomes in venoarterial extracorporeal membrane oxygenation

A Diehl, AJC Burrell, AA Udy, PMA Alexander… - Critical care …, 2020 - journals.lww.com
Objectives: The manipulation of arterial carbon dioxide tension is associated with differential
mortality and neurologic injury in intensive care and cardiac arrest patients; however, few …

Critical care of the post–cardiac arrest patient

AC Walker, NJ Johnson - Cardiology clinics, 2018 - cardiology.theclinics.com
Sudden cardiac arrest affects more than 500,000 people in the United States each year.
Patients who achieve return of spontaneous circulation (ROSC) after cardiac arrest often …

Clinical Phenotyping of Out-of-Hospital Cardiac Arrest Patients With Shockable Rhythm―Machine Learning-Based Unsupervised Cluster Analysis―

Y Okada, S Komukai, T Kitamura, T Kiguchi… - Circulation …, 2022 - jstage.jst.go.jp
Background: The hypothesis of this study is that latent class analysis could identify the
subphenotypes of out-of-hospital cardiac arrest (OHCA) patients associated with the …

The effects of arterial CO2 on the injured brain: two faces of the same coin

DA Godoy, M Rovegno, C Lazaridis, R Badenes - Journal of Critical Care, 2021 - Elsevier
Serum levels of carbon dioxide (CO 2) closely regulate cerebral blood flow (CBF) and
actively participate in different aspects of brain physiology such as hemodynamics …