Mucormycosis is an infection caused by a group of filamentous molds within the order
Mucorales. Infections may result from ingestion of contaminated food, inhalation of spores …

Invasive mucormycosis is a life-threatening fungal infection that most frequently occurs in
patients with underlying comorbidities impacting immune system function. 1–4 Rhino-orbital …

Background Early diagnosis and prompt initiation of specific antifungal treatment are
essential for improving the prognosis of mucormycosis. We aimed to assess the …

CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and
mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is …

Mucormycosis is a deadly opportunistic disease caused by a group of fungus named
mucormycetes. Fungal spores are normally present in the environment and the immune …

The triazole scaffold is a key element in heterocyclic chemistry, giving a fundamental
building block in organic, medicinal chemistry, and material science chemistry. Triazole …

Introduction Invasive fungal infections continue to be important causes of morbidity and
mortality in severely ill and immunocompromised patient populations. The past three …

There are four major classes of antifungals with the predominant mechanism of action being
targeting of cell wall or cell membrane. As in other drugs, low solubility of these compounds …

Invasive aspergillosis (IA) is associated with significant morbidity and mortality. Voriconazole
remains the drug of choice for the treatment of IA in children; however, the complex kinetics …

Candida tropicalis is a prominent non-Candida albicans Candida species involved in cases
of candidemia, mainly causing infections in patients in intensive care units and (or) those …