Psoriasis is a chronic inflammatory skin disease. Emerging evidence shows that neurogenic
inflammation, induced by nociceptive neurons and T helper 17 cell (Th17) responses, has a …

Orofacial pain is a universal predicament, afflicting millions of individuals worldwide.
Research on the molecular mechanisms of orofacial pain has predominately focused on the …

Temporomandibular disorder (TMD) pain that involves inflammation and injury in the
temporomandibular joint (TMJ) and/or masticatory muscle is the most common form of …

Background: Neuromedin B (Nmb) is implicated in the regulation of nociception of sensory
neurons. However, the underlying cellular and molecular mechanisms remain unknown …

Background Chronic orofacial pain is a serious public health problem with a prevalence of 7–
11% in the population. This disorder has different etiologies and characteristics that make …

Paclitaxel (PTX) serves as a primary chemotherapy agent against diverse solid tumors
including breast cancer, lung cancer, head and neck cancer and ovarian cancer, having …

This study analyzed the effects of photobiomodulation (PBM) with low-level laser therapy on
nociceptive behavior and neuronal activity in the trigeminal nucleus after experimental …

The pathology of migraine, a common neurological disease, involves sensitization and
activation of trigeminal nociceptive neurons to promote hyperalgesia and allodynia during …

Objectives Acute and chronic orofacial pain are very common and remain a vexing health
problem that has a negative effect on the quality of life. Serotonin (5‐HydroxyTryptamine, 5 …

This study aimed to evaluate the effects of inhibitors of the fractalkine pathway in
hyperalgesia in inflammatory and neuropathic orofacial pain in male rats and the …