Structure and function of small airways in asthma patients revisited

WB van den Bosch, AL James… - European Respiratory …, 2021 - Eur Respiratory Soc
Small airways (< 2 mm in diameter) are probably involved across almost all asthma
severities and they show proportionally more structural and functional abnormalities with …

[HTML][HTML] Articular cartilage repair biomaterials: strategies and applications

M Wang, Y Wu, G Li, Q Lin, W Zhang, H Liu, J Su - Materials Today Bio, 2024 - Elsevier
Articular cartilage injury is a frequent worldwide disease, while effective treatment is urgently
needed. Due to lack of blood vessels and nerves, the ability of cartilage to self-repair is …

Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial …

MS Eapen, W Lu, TL Hackett, GK Singhera… - ERJ open …, 2021 - Eur Respiratory Soc
Introduction Previous reports have shown epithelial–mesenchymal transition (EMT) as an
active process that contributes to small airway fibrotic pathology. Myofibroblasts are highly …

Airway luminal area and the resistive work of breathing during exercise in healthy young females and males

CM Peters, MG Leahy, G Hohert… - Journal of Applied …, 2021 - journals.physiology.org
We examined the relationship between the work of breathing (Wb) during exercise and in
vivo measures of airway size in healthy females and males. We hypothesized that sex …

Fully integrating pathophysiological insights in COPD: an updated working disease model to broaden therapeutic vision

EH Walters, SD Shukla, MQ Mahmood… - European Respiratory …, 2021 - Eur Respiratory Soc
Our starting point is that relatively new findings into the pathogenesis and pathophysiology
of airway disease in smokers that lead to chronic obstructive pulmonary disease (COPD) …

Structural features on quantitative chest computed tomography of patients with maximal mid-expiratory flow impairment in a normal lung function population

Y Yang, H Ge, J Lu, X Huang, K Wang, L Jin… - BMC Pulmonary …, 2023 - Springer
Background Maximal mid-expiratory flow (MMEF) is an earlier predictor of chronic
obstructive pulmonary disease (COPD) development than forced expiratory volume in 1 s …

Airway morphological abnormalities of bronchiolitis assessed by endobronchial optical coherence tomography

ZQ Su, ML Zhong, MY Fan, WY Rao… - Therapeutic …, 2023 - journals.sagepub.com
Background: A few studies have reported the medium-sized and small airway morphological
abnormalities of bronchiolitis. Whether spirometry or impulse oscillometry (IOS) is correlated …

A Dual Functional Bioinspired Lubricant for Osteoarthritis Treatment and Potential Prevention

R Yan, H Yang, Y Liu, Y Wang, S Liu… - ACS Applied Materials …, 2024 - ACS Publications
Osteoarthritis (OA), primarily characterized by the deterioration of articular cartilage, is a
highly prevalent joint-disabling disease. The pathological onset and progression of OA are …

Small airway dysfunction in pneumoconiosis: a cross-sectional study

Y Fan, R Ma, X Du, D Chai, S Yang, Q Ye - BMC Pulmonary Medicine, 2022 - Springer
Background Although several histological studies have documented airway inflammation
and remodelling in the small airways of dust-exposed workers, little is known regarding the …

[HTML][HTML] Endobronchial optical coherence tomography or computed tomography for evaluating progression of bronchiectasis

L Cheng, W Guan, C Zhong, C Duan, Z Su… - ERJ Open …, 2023 - Eur Respiratory Soc
Background The early radiological signs of progression in bronchiectasis remain unclear.
The objective of the present study was to compare endobronchial optical coherence …