The incidence of obesity and overweight has reached epidemic levels in the United States
and developed countries worldwide. Even more alarming is the increasing prevalence of …

The completion of draft sequences of the human genome represented a remarkable
achievement for automated DNA sequencing based on Sanger technology. However, the …

Cross-sex hormone therapy (CHT) is critical for phenotypical and physiological transition in
adults with gender dysphoria (GD). However, the impact of the CHT onto the molecular …

Prenatal stress (PRS) had a long-term adverse effect on motor behaviors. Corticostriatal
synaptic plasticity, a cellular basis for motor controlling, has been proven to participate in the …

Adverse environmental conditions such as UV radiation induce oxidative and aging events
leading to severe damage to human skin cells. Natural products such as plant extracts have …

Methylation catalyzed by the DNAmethyltransferases affects the C5 position of cytosine
residues in DNA. This physiological process is active from the embryo conception …

Regarding oral squamous cell carcinoma (OSCC) development, chewing areca is known to
be a strong risk factor in many Asian cultures. Therefore, we established an OSCC induced …

Methylenetetrahydrofolate reductase gene (MTHFR) C677T polymorphism may be a risk
factor for head and neck squamous cell carcinoma due to changes in folate levels that can …

Background Silencing of tumor suppressor genes plays a vital role in head and neck
carcinogenesis. The purposes of this study were to determine the methylation profile of …

Squamous cell carcinomas (SqCCs) arise in a wide range of tissues including skin, lung,
and oral mucosa. Although all SqCCs are epithelial in origin and share common …