[HTML][HTML] Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

Advances in RT-LAMP for COVID-19 testing and diagnosis

G Choi, TJ Moehling, RJ Meagher - Expert Review of Molecular …, 2023 - Taylor & Francis
ABSTRACT Introduction The SARS-CoV-2 pandemic, and the subsequent limitations on
standard diagnostics, has vastly expanded the user base of Reverse Transcription Loop …

Glow-in-the-dark infectious disease diagnostics using Crispr-Cas9-based Split luciferase complementation

HJ van der Veer, EA van Aalen… - ACS Central …, 2023 - ACS Publications
Nucleic acid detection methods based on CRISPR and isothermal amplification techniques
show great potential for point-of-care diagnostic applications. However, most current …

[HTML][HTML] Real-life performance of a COVID-19 rapid antigen detection test targeting the SARS-CoV-2 nucleoprotein for diagnosis of COVID-19 due to the Omicron …

P de Michelena, I Torres, Á Ramos-García… - The Journal of …, 2022 - ncbi.nlm.nih.gov
To the Editor, Rapid antigen detection tests (RADT) targeting the SARS-CoV-2 nucleocapsid
protein (NP) displaying a sensitivity over 80% have been proven useful for early diagnosis of …

[HTML][HTML] SMART-LAMP: A smartphone-operated handheld device for real-time colorimetric point-of-care diagnosis of infectious diseases via loop-mediated isothermal …

J García-Bernalt Diego, P Fernández-Soto… - Biosensors, 2022 - mdpi.com
Nucleic acid amplification diagnostics offer outstanding features of sensitivity and specificity.
However, they still lack speed and robustness, require extensive infrastructure, and are …

[HTML][HTML] The future of point-of-care nucleic acid amplification diagnostics after COVID-19: time to walk the walk

J García-Bernalt Diego, P Fernández-Soto… - International Journal of …, 2022 - mdpi.com
Since the onset of the COVID-19 pandemic, over 610 million cases have been diagnosed
and it has caused over 6.5 million deaths worldwide. The crisis has forced the scientific …

[HTML][HTML] Kidney injury associated with COVID-19 infection and vaccine: A narrative review

ICR Pacheco, DMN Costa, DS Sousa… - Frontiers in …, 2022 - frontiersin.org
The respiratory tract is the main infection site for severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), resulting in many admissions to intensive care centers in …

Extreme differences in SARS-CoV-2 viral loads among respiratory specimen types during presumed pre-infectious and infectious periods

A Viloria Winnett, R Akana, N Shelby, H Davich… - PNAS …, 2023 - academic.oup.com
Abstract SARS-CoV-2 viral-load measurements from a single-specimen type are used to
establish diagnostic strategies, interpret clinical-trial results for vaccines and therapeutics …

COVID-19 Rapid Antigen Tests With Self-Collected vs Health Care Worker–Collected Nasal and Throat Swab Specimens: A Randomized Clinical Trial

T Todsen, KK Jakobsen, MP Grønlund… - JAMA network …, 2023 - jamanetwork.com
Importance Self-or health care worker (HCW)–collected nasal swab specimens are the
preferred sampling method to perform rapid antigen testing for COVID-19, but it is debated …

Impact of community asymptomatic rapid antigen testing on covid-19 related hospital admissions: synthetic control study

X Zhang, B Barr, M Green, D Hughes, M Ashton… - bmj, 2022 - bmj.com
Objective To analyse the impact of voluntary rapid testing for SARS-CoV-2 antigen in
Liverpool city on covid-19 related hospital admissions. Design Synthetic control analysis …