Tissue clearing
DS Richardson, W Guan, K Matsumoto, C Pan… - Nature Reviews …, 2021 - nature.com
Tissue clearing of gross anatomical samples was first described more than a century ago
and has only recently found widespread use in the field of microscopy. This renaissance has …
and has only recently found widespread use in the field of microscopy. This renaissance has …
Nano-delivery to the lung-by inhalation or other routes and why nano when micro is largely sufficient?
V Forest, J Pourchez - Advanced Drug Delivery Reviews, 2022 - Elsevier
Respiratory diseases gather a wide range of disorders which are generally difficult to treat,
partly due to a poor delivery of drugs to the lung with adequate dose and minimum side …
partly due to a poor delivery of drugs to the lung with adequate dose and minimum side …
Advances in ex situ tissue optical clearing
P Matryba, L Kaczmarek, J Gołąb - Laser & Photonics Reviews, 2019 - Wiley Online Library
Examination of whole organs with subcellular resolution in health, disease, and during
development is necessary to decipher their biological complexity. However, until recently …
development is necessary to decipher their biological complexity. However, until recently …
Revisiting airflow and aerosol transport phenomena in the deep lungs with microfluidics
J Sznitman - Chemical Reviews, 2021 - ACS Publications
The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …
[HTML][HTML] Effects of physicochemical properties of TiO2 nanomaterials for pulmonary inflammation, acute phase response and alveolar proteinosis in intratracheally …
PH Danielsen, KB Knudsen, J Štrancar, P Umek… - Toxicology and Applied …, 2020 - Elsevier
Nanomaterial (NM) characteristics may affect the pulmonary toxicity and inflammatory
response, including specific surface area, size, shape, crystal phase or other surface …
response, including specific surface area, size, shape, crystal phase or other surface …
Nanoparticle delivery systems with cell-specific targeting for pulmonary diseases
Respiratory disorders are among the most important medical problems threatening human
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …
Innovative preclinical models for pulmonary drug delivery research
Introduction: Pulmonary drug delivery is a complex field of research combining physics
which drive aerosol transport and deposition and biology which underpins efficacy and …
which drive aerosol transport and deposition and biology which underpins efficacy and …
[HTML][HTML] Pulmonary inhalation for disease treatment: Basic research and clinical translations
B Wang, L Wang, Q Yang, Y Zhang, T Qinglai, X Yang… - Materials Today Bio, 2024 - Elsevier
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with
few systemic side effects. In addition, it is non-invasive and has good patient compliance …
few systemic side effects. In addition, it is non-invasive and has good patient compliance …
Pulmonary delivery of size-transformable nanoparticles improves tumor accumulation and penetration for chemo-sonodynamic combination therapy
Very little is currently known about how inhaled nanomedicine for lung cancer treatment
overcomes biological barriers hampering the tumor availability of drug and nanoparticles …
overcomes biological barriers hampering the tumor availability of drug and nanoparticles …
Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline
A Artzy-Schnirman, N Hobi, N Schneider-Daum… - European Journal of …, 2019 - Elsevier
With rapid advances in micro-fabrication processes and the availability of biologically-
relevant lung cells, the development of lung-on-chip platforms is offering novel avenues for …
relevant lung cells, the development of lung-on-chip platforms is offering novel avenues for …