Antimicrobial resistance in ESKAPE pathogens

DMP De Oliveira, BM Forde, TJ Kidd… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …

Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae

M Rozwandowicz, MSM Brouwer… - Journal of …, 2018 - academic.oup.com
Bacterial antimicrobial resistance (AMR) is constantly evolving and horizontal gene transfer
through plasmids plays a major role. The identification of plasmid characteristics and their …

[HTML][HTML] Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome

SC Forster, J Liu, N Kumar, EL Gulliver… - Nature …, 2022 - nature.com
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …

The epidemiology of carbapenem-resistant Enterobacteriaceae: the impact and evolution of a global menace

LK Logan, RA Weinstein - The Journal of infectious diseases, 2017 - academic.oup.com
Carbapenem-resistant Enterobacteriaceae (CRE) are a serious public health threat.
Infections due to these organisms are associated with significant morbidity and mortality …

Global epidemiology of CTX-M β-lactamases: temporal and geographical shifts in genotype

ER Bevan, AM Jones, PM Hawkey - Journal of antimicrobial …, 2017 - academic.oup.com
Globally, rates of ESBL-producing Enterobacteriaceae are rising. We undertook a literature
review, and present the temporal trends in bla CTX-M epidemiology, showing that bla CTX …

[HTML][HTML] Extended-spectrum β-lactamase-producing Enterobacteriaceae: update on molecular epidemiology and treatment options

G Peirano, JDD Pitout - Drugs, 2019 - Springer
Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are a major global
public health concern. Presently, Escherichia coli with CTX-Ms are the most common …

[HTML][HTML] Escherichia coli as a Multifaceted Pathogenic and Versatile Bacterium

VS Braz, K Melchior, CG Moreira - Frontiers in cellular and infection …, 2020 - frontiersin.org
Genetic plasticity promotes evolution and a vast diversity in Escherichia coli varying from
avirulent to highly pathogenic strains, including the emergence of virulent hybrid …

The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae

AJ Mathers, G Peirano, JDD Pitout - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in
the 2000s as important human pathogens, have spread extensively throughout the world …

The global ascendency of OXA-48-type carbapenemases

JDD Pitout, G Peirano, MM Kock… - Clinical microbiology …, 2019 - Am Soc Microbiol
Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …