Psoriasis is a chronic inflammatory multi organ disease with well characterized pathology
occurring in the skin and often the joints. Although the disease has many characteristic and …

Psoriasis is now classified as an immune-mediated inflammatory disease (IMID) of the skin.
It is being recognized that patients with various IMIDs, including psoriasis, are at higher risk …

Background The interleukin‐17 cytokine family plays a central role in psoriasis
pathogenesis. Objectives To evaluate the efficacy and safety of brodalumab, a human anti …

Psoriasis is one of the most common human skin diseases and is considered to have key
genetic underpinnings. It is characterized by excessive growth and aberrant differentiation of …

The importance of T helper 17 (Th17) cells in inflammation and autoimmunity is now being
appreciated. We analyzed psoriasis skin lesions and peripheral blood for the presence of IL …

Glucocorticoid synthesis is a complex, multistep process that starts with cholesterol being
delivered to the inner membrane of mitochondria by StAR and StAR-related proteins. Here …

A genome-wide association study was performed to identify genetic factors involved in
susceptibility to psoriasis (PS) and psoriatic arthritis (PSA), inflammatory diseases of the skin …

Psoriasis is a chronic immune-mediated hyperproliferative inflammatory skin disease in
which a cytokine network concept is well established. Skin is a major target of oxidative …

Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis vulgaris, with an
estimated prevalence of 1%–2.25% among psoriatic patients. The condition presents with …

Psoriasis may be associated with dyslipidaemia, a known risk factor for cardiovascular
disease. This systematic review aims to synthesize evidence for the association between …