Recent advances in the pharmacologic treatment of spinal cord injury

A Cox, A Varma, N Banik - Metabolic brain disease, 2015 - Springer
A need exists for the effective treatment of individuals suffering from spinal cord injury (SCI).
Recent advances in the understanding of the pathophysiological mechanisms occurring in …

[HTML][HTML] Anti-inflammatory and antiviral effects of minocycline in enterovirus 71 infections

YT Liao, SM Wang, SH Chen - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract Enterovirus 71 (EV71) brainstem encephalitis (BE) is divided into—uncomplicated
BE, autonomic nervous system (ANS) dysregulation, and pulmonary edema (PE)—based on …

Delayed xenon post-conditioning mitigates spinal cord ischemia/reperfusion injury in rabbits by regulating microglial activation and inflammatory factors

Y Yang, Y Wang, J Lu, L Tian, M Jin… - Neural Regeneration …, 2018 - journals.lww.com
The neuroprotective effect against spinal cord ischemia/reperfusion injury in rats exerted by
delayed xenon post-conditioning is stronger than that produced by immediate xenon post …

Simultaneous investigation of hemodynamic, microcirculatory and arterio-venous micro-rheological parameters in infrarenal or suprarenal aortic cross-clamping …

N Nemeth, F Kiss, Z Klarik, E Toth… - Clinical …, 2014 - content.iospress.com
We aimed to investigate hemodynamic, microcirculatory and hemorheological consequence
of infrarenal or suprarenal aortic cross-clamping (IRAXC, SRAXC) in the rat. We …

Minocycline effectively protects the rabbit's spinal cord from aortic occlusion-related ischemia

B Drenger, Y Fellig, D Ben-David, B Mintz… - … of Cardiothoracic and …, 2016 - Elsevier
Objectives To identify the minocycline anti-inflammatory and antiapoptotic mechanisms
through which it is believed to exert spinal cord protection during aortic occlusion in the …

Minocycline before aortic occlusion reduces hindlimb motor impairment, attenuates spinal cord damage and spinal astrocytosis, and preserve neuronal …

B Drenger, TJJ Blanck, B Piskoun, E Jaffrey… - … of Cardiothoracic and …, 2019 - Elsevier
Objectives Spinal cord ischemia secondary to trauma or a vascular occlusive event is a
threatening phenomenon. The neuroprotective properties of minocycline have been shown …

Inflammation as a target of minocycline: special interest in the regulation of inflammasome signaling

A Kauppinen, A Salminen, K Kaarniranta - Inflammasome, 2014 - access.portico.org
Minocycline is a wide-spectrum antibiotic derived from tetracycline. In addition to its anti-
microbial activity, minocycline is known to possess several immunomodulatory and …

氙气延迟后处理减轻兔脊髓缺血再灌注损伤: 小胶质细胞活化炎性因子调控

Y Yang, Y Wang, J Lu, L Tian, M Jin… - 中国神经再生研究(英文 …, 2018 - sjzsyj.com.cn
课题组前期研究证实氙气延迟后处理对大鼠脊髓缺血再灌注损伤的保护作用明显强于氙气即刻
后处理, 但机制不明. 小胶质细胞是神经系统中主要的炎症细胞之一, 激活后释放促炎因子可导致 …

[引用][C] The disease ameliorating effects of minocycline in neurologic disorders

S Kapoor - Journal of Cardiothoracic and Vascular Anesthesia, 2013 - jcvaonline.com
1. Elsayed H, McKevith J, McShane J, et al: Thoracic epidural or paravertebral catheter for
analgesia after lung resection: is the outcome different? J Cardiothorac Vasc Anesthesia 26 …