[HTML][HTML] Calcitonin Gene-Related Peptide-Mediated Trigeminal Ganglionitis: The Biomolecular Link between Temporomandibular Disorders and Chronic Headaches
L Sangalli, B Eli, S Mehrotra, S Sabagh… - International Journal of …, 2023 - mdpi.com
A bidirectional causal relationship has been established between temporomandibular
disorders (TMDs) and chronic headaches. Recent advances in the neurobiology of chronic …
disorders (TMDs) and chronic headaches. Recent advances in the neurobiology of chronic …
Trigeminal somatosensation in the temporomandibular joint and associated disorders
SK Perry, JJ Emrick - Frontiers in Pain Research, 2024 - frontiersin.org
The temporomandibular joint (TMJ) consists of bone, cartilage, ligaments, and associated
masticatory muscles and tendons that coordinate to enable mastication in mammals. The …
masticatory muscles and tendons that coordinate to enable mastication in mammals. The …
[HTML][HTML] Vitexin inhibits pain and itch behavior via modulating TRPV4 activity in mice
Z Qin, L Xiang, S Zheng, Y Zhao, Y Qin, L Zhang… - Biomedicine & …, 2023 - Elsevier
Itching and pain are distinct unpleasant sensations. The transient receptor potential cation
channel subfamily V member 4 (TRPV4) pathway is regarded as a shared pathway that …
channel subfamily V member 4 (TRPV4) pathway is regarded as a shared pathway that …
PAR2-dependent phosphorylation of TRPV4 at the trigeminal nerve terminals contributes to tongue cancer pain
R Akasaka, A Furukawa, Y Hayashi, S Hitomi… - Journal of Oral …, 2023 - Elsevier
Objective This study aimed to clarify the interactions between the tongue and primary
afferent fibers in tongue cancer pain. Methods A pharmacological analysis was conducted to …
afferent fibers in tongue cancer pain. Methods A pharmacological analysis was conducted to …
[HTML][HTML] TMEM100, a regulator of TRPV1-TRPA1 interaction, contributes to temporomandibular disorder pain
There is an unmet need to identify new therapeutic targets for temporomandibular disorder
(TMD) pain because current treatments are limited and unsatisfactory. TMEM100, a two …
(TMD) pain because current treatments are limited and unsatisfactory. TMEM100, a two …
Silencing of TRPV4-expressing sensory neurons attenuates temporomandibular disorders pain
Identification of potential therapeutic targets is needed for temporomandibular disorders
(TMD) pain, the most common form of orofacial pain, because current treatments lack …
(TMD) pain, the most common form of orofacial pain, because current treatments lack …
[HTML][HTML] CGRP neuropeptide levels in patients with endometriosis-related pain treated with dienogest: a comparative study
S Chaichian, ZD Firoozabadi, S Rokhgireh… - BMC Women's …, 2024 - Springer
Background and objective Endometriosis (EM) involves the peripheral nervous system and
causes chronic pain. Sensory nerves innervating endometriotic lesions contribute to chronic …
causes chronic pain. Sensory nerves innervating endometriotic lesions contribute to chronic …
[HTML][HTML] Expression of CGRP in the Trigeminal Ganglion and Its Effect on the Polarization of Macrophages in Rats with Temporomandibular Arthritis
J Tao, X Wang, J Xu - Cellular and Molecular Neurobiology, 2024 - Springer
Calcitonin gene-related peptide (CGRP) is synthesized and secreted by trigeminal ganglion
neurons, and is a key neuropeptide involved in pain and immune regulation. This study …
neurons, and is a key neuropeptide involved in pain and immune regulation. This study …
Nitrogen-Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors for Treating Pain and Cardiovascular Diseases
RW Sabnis - ACS Medicinal Chemistry Letters, 2023 - ACS Publications
Nitrogen-Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors for
Treating Pain and Cardiovascular Diseases Page 1 Nitrogen-Containing 2,3-Dihydroquinazolinone …
Treating Pain and Cardiovascular Diseases Page 1 Nitrogen-Containing 2,3-Dihydroquinazolinone …
Calcitonin gene‐related peptide and persistent corneal pain: A trigeminal nerve sensitization perspective
X Hong, F Ding, J Xiong, Y Wu, W Chen - Brain‐X, 2023 - Wiley Online Library
Persistent corneal pain (PCP) has excellent research prospects, especially the central
sensitization mechanism of the trigeminal nerve, which is involved in migraine, corneal pain …
sensitization mechanism of the trigeminal nerve, which is involved in migraine, corneal pain …