Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …

Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

GINA no longer recommends treating adults/adolescents with asthma with short-acting
bronchodilators alone. Instead, they should receive symptom-driven (in mild asthma) or a …

Building on the success of the 14 previous editions, this remarkable reference has been
extensively reorganized and expanded and now comprises almost 1,500 individual drug …

Background The role of long-acting, inhaled β2-agonists in treating asthma is uncertain. In a
double-blind study, we evaluated the effects of adding inhaled formoterol to both lower and …

BACKGROUND: The goals of asthma treatment include preventing recurrent exacerbations.
Yet there is no consensus about the terminology for describing or defining “exacerbation” or …

The optimal treatment for mild asthma is uncertain. We assessed the effects of adding a long-
acting inhaled beta-agonist, formoterol, to low doses of an inhaled corticosteroid …

Background: A clinical model is needed to compare inhaled corticosteroids (ICSs) with
respect to efficacy. Objective: The purpose of this investigation was to compare the relative …

The human β2-adrenergic receptor gene has multiple single-nucleotide polymorphisms
(SNPs), but the relevance of chromosomally phased SNPs (haplotypes) is not known. The …

Although consensus has emerged from the clinical, social science, psychological, and
biological literature that psychosocial factors aVect asthma morbidity in children, their role in …